Localized hyperthermia ultrasound

During hyperthermia, terms representing the heat input to a specific tissue or whole body must be added to the proper system equation(s). For example, during whole-body or local hyperthermia induced by radiofrequency currents, microwaves, or ultrasound, a heat-generation term is added to the section of the body being heated. During hyperthermia with blood perfusion, the afferent blood temperature is set at a desired value, and the efferent blood is circulated to the central blood pool, or to the extracorporeal device used for heating the blood. Suitable numerical... 

Heat is one of the most efficient weapons to destroy tumor cells. But to induce a moderate heat of 41-47°C for a short duration (5-10 min) in the body without affecting normal tissue is quite difficult. Some of the commonly used heating sources to induce localized hyperthermia in the body are radiofrequency (RF), microwaves, ultrasound, magnetic field, and light [24]. 

Fessenden P, Lee ER, Anderson TL, Strohbehn JW, Meyer JL, Samulski TV, Marmor JB (1984) Experience with a multitransducer ultrasound system Iot localized hyperthermia of deep tissues. IEEE Trans Biomed Eng 31 126-135... 

Local hyperthermia uses very high heat. Radio waves, microwaves, ultrasound waves, and other forms of energy can be used to heat the local area. When ultrasound is used, the technique is called high intensity focused ultrasound, or HIFU. The heat may be applied using different methods ... 

Ultrasound in Cancer Therapy The use of ultrasound to enhance cancer therapy has been the subject of numerous biological and clinical investigations. In most of these studies, ultrasound has been used as an agent to induce hyperthermia for either direct treatment of small and localized cancerous tumors20-27 or as adjuvant therapy to increase the efficacy of radiotherapy and chemotherapy. 

Andronova, N.V, Bokhyan, B.Yu., Nikolaev, A.L., Treschahna, E.M., Aliev, M.D., Kovalevskiy, E.E., Filonenko, D.V, Gopin, A.V., Bozhevolnov, V.E., Kogan, B.Ya., Vorozhtsov, G.N. Rationale for clinical study of preoperative treatment of soft hssue sarcomas with local ultrasound hyperthermia and chemotherapy with cisplatin and/or doxorubicin. Sarcoma of bone, soft tissue and skin tumors, 2011, 1, 28-33 (in Russian). 

Salomir, R., F. C. Vimeux, J. A. de Zwart, N. Grenier, and C. T. W. Moonen, Hyperthermia by MR-Guided Focused Ultrasound Accurate Temperature Control Based on Fast MRI and a Physical Model of Local Energy Deposition and Heat Conduction, Magnetic Resonance in Medicine, 43,342 (2000). 

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