Glycogen liver

Cortisone is a hormone produced by the cortex of the adrenal glands. As with other adrenal corticoid steroids, administration of cortisone leads to an increased deposition of liver glycogen. Tt can remove features of rheumatoid arthritis, but does not check the underlying disease it is used in various diseases of the eye, and is an antiallergic and anlifibroplastic agent. 

Stalmans, W., Cadefau, J., Wera, S., and Bollen, M., 1997. New insight into die reguladon of liver glycogen metabolism by glucose. Biochemical Society Transactions 25 19—25. 

Even though acetate units, such as those obtained from fatty acid oxidation, cannot be used for net synthesis of carbohydrate in animals, labeled carbon from " C-labeled acetate can be found in newly synthesized glucose (for example, in liver glycogen) in animal tracer studies. Explain how this can be. Which carbons of glucose would you expect to be the first to be labeled by "Relabeled acetate ... 

Hultman, E. Nilsson, L.H. (1971). Liver glycogen in man. Effect of different diet and muscular exercise. In Muscle Metabolism During Exercise (Pemow, B. Saltm, B., eds.), pp. 143-151, Plenum Press, New York. 

Nilsson, L.H. Hultman, E. (1973). Liver glycogen in man. The effect of total starvation or a carbohydrate-poor diet followed by carbohydrate refeeding. Scand. J. Clin. Lab. Invest. 32, 325-330. 

Metab 12.5 F (increased blood glucose decreased liver glycogen)... 

Figure 18-3. The biosynthesis of glycogen. The mechanism of branching as revealed by adding "C-labeled glucose to the diet in the living animal and examining the liver glycogen at further intervals.

McGarry JD et al From dietary glucose to liver glycogen the full circle round. Annu RevNutr 1987 7 51. 

Glucose is also formed from liver glycogen by glycogenolysis (Chapter 18). 

Completely negative results on the formation of liver glycogen were obtained when the sodium salts of caproic or caprylic acid61 60 were fed, as well as after the administration of the ethyl esters of caproic, caprylic, capric, myristic or oleic acids or methyl laurate.81 Caproic acid was found to be ineffective as a D-glucose-former in the phlorizinized dog.89... 

The effect of alkali treatment on molecular weight (compare with the case of the starch components) has been studied treating a 5% solution of rabbit-liver glycogen in 2 N sodium hydroxide, for 90 minutes at 100°, decreased the sedimentation constant (Sits X 1013) from 86 to 57 (that is, by 34%).237... 

Exposed to 19, 32 or 51 mg/L for up to 96 h Dose- and time-dependent increase in blood glucose and lactic acid concentrations liver glycogen decreased at all nickel levels and muscle glycogen decreased at the two higher levels high nickel concentrations were associated with elevated erythrocyte number, hemoglobin, and hematocrit. Nickel accumulated in blood, liver, muscle, and especially in kidney 41... 

Juveniles 65,000 LC50 (96 h) liver glycogen reduced BCF of 22 in whole fish 60... 

Bengeri, K.V. and H.S. Patil. 1986. Respiration, liver glycogen and bioaccumulation in Labeo mhita exposed to zinc. Indian Jour. Comp. Anim. Physiol. 4 79-84. 

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