Liver failure cerebral edema

Unfortunately, the development of brain edema can hardly be monitored in patients with acute liver failure. Brain edema mostly occurs when hepatic encephalopathy has progressed to grades III to IV. In grades I-II encephalopathy, it has rarely been observed. With progression to grade III HE cerebral edema occurs in up to 35% and with grade IV HE in 65 to 75% of the patients (Munoz, 1993). 

Two cases of serious or fatal toxicity have been described in two infants who had been treated with herbal tea containing pennyroyal oil (4). One infant developed fulminant liver failure with cerebral edema and necrosis the other infant developed hepatic dysfunction and a severe epileptic encephalopathy. 

Cerebral malaria Cognitive impairment Gastroenteritis Hypoglycemia Liver failure Metabolic acidosis Noncardiac pulmonary edema Pregnancy ... 

Prognosis of acute liver failure depends on several factors like etiology of liver disease, age, grade of liver disease, grade of encephalopathy, presence or absence of systemic inflammatory response syndrome, etc. Currently available prognostic scoring systems do not adequately predict outcomes or determine candidacy for liver transplantation (Poison and Lee, 2005). In the smdy of Bhatia et al. (2006), however, three variables were found to be significantly predictive of death arterial ph > 7.40, presence of clinical cerebral edema, and arterial ammonia levels > 124 [imol/1. 

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