Lithium distribution

Heurteaux C, Baumann N, Lachapelle F, et al Lithium distribution in the brain of normal mice and of quacking dysmyelinating mutants. J Neurochem 46 1317-1321, 1986... 

Smith DF Lithium attenuates clonidine-induced hypoactivity further studies in in-bred mouse strains. Psychopharmacology 94 428-430, 1988 Smith DF, Amdisen A Lithium distribution in rat brain after long-term central administration by minipump. J Pharm Pharmacol 33 805-806, 1981 Smith J, Williams K, Birkett S, et al Neuroendocrine and clinical effects of electroconvulsive therapy and their relationship to treatment outcome. Psychol Med 24 547-555, 1994... 

X-ray Photoelectron Spectroscopy (XPS) and Laser Ion Induced Mass Analysis (LIMA) were used to investigate samples of catalyst A. These techniques can show the extent of potassium and lithium distribution within individual catalyst pellets. Samples that had been subjected to 50,100, and 1000 hours of steam reforming in a molten carbonate environment were analysed. A fresh sample of the catalyst was also examined for purposes of comparison. 

Tissue lithium distribution in rat after chronic administration of 1 mmol/kg in drinking fluid... 

The microlocalisation technique with the stable isotope Li uses a beam of neutrons in an atomic reactor. The Li nucleus absorbs a neutron and immediately undergoes fission to produce an a-particle and a H atom, which create tracks in a suitable detector placed in contact with Li-containing tissue. The tissue distribution in the rat, brain lithium distribution in the mouse " and the rat, ° distribution in the mouse embryo, kinetics in the mouse brain, and distribution in mutant strains of mice with dysmyelination have been studied. 

Figure 6 Partitioning of LiCl between water and 1-octanol at 25°C, as taken from ref. [2l6]. The lithium distribution ratios Du were determined at 1 1 initial phase ratio by use of ion chromatography (IC), inductively coupled plasma (ICP) atomic emission spectrometry, and Li NMR spectrometry. A correction was made for the slight volume changes due to the mutual solubility of 1-octanol and water. Error bars are indicated only for the ICP data, which were the least precise data obtained by the three techniques. The solid curved line represents the equilibrium model calculated by SXLSQl using the values of log/Cs= = —6.85 and logX, = — 2.74 (Table 12). The dashed curved line is an extrapolation of the model to indicate the approach to the calculated asymptotic value of the distribution ratio at infinite dilution (3.76 X 10...

A. Acute ingestion may cause initial mild nausea and vomiting, but systemic signs of intoxication are minimal and usually are delayed for several hours while lithium distributes into tissues. Initially high semm levels fall by 50-70% or more with tissue equilibration. 

PHYSIOLOGICAL AND CLINICAL ASPECTS 3.1. Lithium Distribution Determined in Experimentai Animals... 

By applying maximum entropy methods to the diffraction data this analysis obtained a fuller picture of the lithium distribution than could be extracted from a conventional refinement of the structure. 

The lithium distribution in red blood cells has been investigated using Li NMR spectroscopy. Li NMR imaging has been applied to lithium in the brain and muscle of rats. The dipolar interaction of Na with hydrogen nuclei in glycerol solution has been measured.The phase diagram of a lyotropic mixture sodium bis(2-ethylhexyl) sulfosuccinate/dodecanol/water has been studied using Na NMR spectroscopy. Multiple-quantum filtered and Na NMR... 

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