Listeria monocytogenes, motility

Theriot et al., 1992] Theriot, J. A., Mitchison, T. J., Tilney, L. G., and Portnoi, D. A. The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization. Nature. 357 (1992) 257-260... 

Two examples where actin polymerization is observed in eukaryotes are in the bacterial pathogens Listeria monocytogenes and Shigella flexneri. The motion that the eukaryote pathogens exhibit is the actin based motility in the cytoplasm of their host. Actin polymerization is known to occur via an insertion polymerization mechanism. The movement is a result of site-directed tread-milling of the actin filaments. This type of movement is classified as a propulsive type motion. The driving force for actin pol)unerization as well as the next motor is the conversion of adenosine triphosphate (ATP) to adenosine diphosphate (ADP). ... 

Laurent, V., Loisel, T.P., Harbeck, B., Wehman, A., Grobe, L., Jockusch, B.M., Wehland, J., Gertler, E.B. and CarHer, M.E. (1999). Role of proteins of the EnaWASP family in actin-based motility of Listeria monocytogenes. J. Cell Biol. 144, 1245-1258. 

Kuo, S.C. and J.L. McGrath, Steps and fluctuations of listeria monocytogenes during actin-based motility. 

McGrath, J.L., N.J. Eungdamrong, C.l. Fisher, F. Peng, L. Mahadevan, T.J. Mitchison, and S.C. Kuo, The force-velocity relationship for the actin-based motility of Listeria monocytogenes. Curr. Biol, 2003, 13 329-332. 

Robbins, J.R. and J.A. Theriot, listeria monocytogenes rotates around its long axis during actin-based motility. Curr. Biol, 2003, 13 R754—R756. 

Listeria A genus of rod-shaped aerobic motile Gram-positive bacteria. Only one species, L. monocytogenes, causes disease (listeriosis). It is resistant to physical and chemical treatments and can occur as a contaminant in certain foods, in faeces, etc. Listeriosis can take various forms, depending on the site of infection localization in the central nervous system causes meningo-encephaUtis, while uterine infection can result in abortion or congenital handicap in the fetus. 

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