Liquid chromatography/mass spectrometry multiplexed

Nogle, L.M. Mallis, L.M. Utilization of Multiplexed Liquid Chromatography/ Mass Spectrometry in the Purity and Accurate Mass Determination of Pharmaceutical Compound Libraries, in Proceedings ofthe 51st ASMS Conference on Mass Spectrometry and Allied Topics, Quebec, Canada, June 8-12, 2003. 

Mathis, J.A., McCord, B.R. (2005) The analysis of high explosives by liquid chromatography/electrospray ionization mass spectrometry multiplexed detection of negative ion adducts. Commmunications in Mass Spectrometry,19,99-104. 

This chapter will review recent advances in mass spectrometry, liquid chromatography, and sample preparation techniques that aim at achieving high throughput. In particular, online solid phase extraction and multiplexed HPLC front ends for quantitative bioanalysis will be discussed in detail. 

Fang, L. et al. 2003. Parallel high-throughput accurate mass measurement using a nine-channel multiplexed electrospray liquid chromatography ultraviolet time-of-flight mass spectrometry system. Rapid Commun. Mass Spectrom. 17 1425. 

Bayliss M. Little D. Mallett D. Plumb R. Parallel ultra-high flow rate liquid chromatography with mass spectrometric detection using a multiplex electrospray source for direct, sensitive determination of pharmaceuticals in plasma at extremely high-throughput. Rapid Communications in Mass Spectrometry, 2000, 14, 2039-2045. 

Decosterd LA et al (2010) Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidula-fungin, and caspofungin. Antimicrob Agents Chemother 54 5303-5315... 

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