Lipo oligosaccharide

N. P. J. Price and R. W. Carlson, Rhizobial lipo-oligosaccharide nodulation factors multidimensional chromatographic analysis of. symbiotic signals involved in the development of legume root nodules, Glycobiology 5 233 (1995). 

J. Sanjuan, R. W. Carlson, H. P. Spaink, U. R. Bhat, W. M. Barbour, J. Glushka, and G. Stacey, A 2-O-methylfucose moiety is present in the lipo-oligosaccharide nodulation signal of Bradyrliizobitim japonicum. Proc. Natl. Acad. Sci U.S.A. H9 8789 (1992). 

Jacques, M. (1996). Role of lipo-oligosaccharides and lipopolysaccharides in bacterial adherence. Trends Microbiol. 4, 408-409. 

Yin Y-Q, Wang J-S, Luo J-G, Kong L-Y (2009) Novel acylated lipo-oligosaccharides from the tuhers of Ipomoea batatas. Carhohyd Res 344 466... 

Truchet, G., Roche, P., Lerouge, P., Vasse, J., Camut, S., de Billy, F., Prome, J.-C., Denarie, J. (1991). Sulfated lipo-oligosaccharide signals of Rhizobium meliloti elicit root nodule organogenesis in alfalfa. Nature 351, 670-3. 

Hou, Y. and Gu, X. X. (2003) Development of peptide mimotopes of lipo-oligosaccharide from nontypeable Haemophilus influenzae as vaccine candidates. J. Immunol. 170,4373-4379. 

M. Gilleron, J. Vercauteren, and G. Puzo, Lipo-oligosaccharidic antigen from Mycobacterium gastri, complete structure of a novel C4-branched 3,6-didcoxy-alpha-jcy/o-hcxopyranosc, Biochemistry, 22 (1994) 1930-1937. 

Structures of Major Trehalose-Containing Lipo-oligosaccharides of Mycobacterium... 

PDMS of native LOS-I showed a [M + Na]+ ion at m/z 1823, confirming the presence of one of each of C15, C15 OH, and C25 fatty acids per molecule of LOS and fragment ions of mlz 245.6, 477.3, 706.9, 993.9, and 1282.4 supported the evidence for the structure of LOS-I, showing that the fatty acids are present on the terminal 2-O-methyl-glucose of the trehalose unit. Similarly, for the LOS from the unknown Mycobacterium, the location of the acyl functions was confirmed by using PDMS. Thus, a combination of alkylation and degradation techniques and PDMS may be used simultaneously to establish the nature and position of the acyl functions on the lipo-oligosaccharides. 

Linton D, Gilbert M, Hitchen PG, Dell A, Morris HR, Wakarchuk WW, Gregson NA, Wren BW. Phase variation of a f -l,3 galactosyltransferase involved in generation of the gangUoside GMl-Uke lipo-oligosaccharide of Campylobacter jejuni. Mol. Microbiol. 94. 

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