Lipidil - Fenofibrate

Linfolysin - Chlorambucil Linosal - Betamethasone Linostil -Dimetacrine tartrate Linton Haloperidol Linyl - Phentermine HCI Lioresal Baclofen Lipanor - Ciprofibrate Lipenthyl - Fenofibrate Lipentyl - Fenofibrate Lipavil - Clofibrate Lipavlon - Clofibrate Lipenan - Clofibride Lipidax - Fenofibrate Lipidicon - Clofibrate Lipidil - Fenofibrate Lipo - Folic acid Lipo-BC - Inositol... 

Kalivoda et al. in 2012 studied the use of blends of different polymeric carriers to enhance the dissolution rate of the poorly water-soluble model drug fenofibrate via HME technology. Copovidone (COP), polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol copolymer (PVCL-PVAc-PEG) and hypromellose 2910/5 (HPMC) were used as a polymeric carriers. Hot-melt extruded feno-flbrate was evaluated by DSC and x-ray diffractometry. Dissolution studies showed that there was a significant increase in the dissolution rate of the hot-melt extruded fenofibrate compared to the pure drug or physical mixture of drug and polymeric carriers. These researchers reported that the fenofibrate extrudates exhibited a 7.6- to 12.1-fold supersaturation and provided superior dissolution performance than marketed formulations Lipidil and Lipidil -Ter. 

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