Fenofibrates

Fibric Acid Derivatives. Fibtic acid derivatives have been used since the 1960s for control of blood Upid levels. The four most well-known compounds in this class ate fenofibrate, gemfibrozil, clofibrate, and bezafibrate, shown in Table 5. Fenofibrate has been the most popular fibtic acid derivative in Europe, and has mote tecentiy been investigated extensively in clinical trials in the United States (153). Bezafibrate is stmcturaHy related to clofibrate, and has tecentiy been reviewed by Western European and AustraUan clinical trials (154). [Pg.131]

Alprenolol HCl Bromelain Ciprofibrate Clortermine HCl Desonide Fenofibrate Flucloronide Flunisolide Fluocinonide Flurandrenolide Glucagon Gramicidin Hetacillin potassium I proniazid Kebuzone Methyltestosterone Niaprazine Probucol Relaxin Somatotropin Triamcinolone acetonide Acetonitrile... [Pg.1610]

Linfolysin - Chlorambucil Linosal - Betamethasone Linostil -Dimetacrine tartrate Linton Haloperidol Linyl - Phentermine HCI Lioresal Baclofen Lipanor - Ciprofibrate Lipenthyl - Fenofibrate Lipentyl - Fenofibrate Lipavil - Clofibrate Lipavlon - Clofibrate Lipenan - Clofibride Lipidax - Fenofibrate Lipidicon - Clofibrate Lipidil - Fenofibrate Lipo - Folic acid Lipo-BC - Inositol... [Pg.1713]

PPARa Liver, heart, skeletal muscle, atherosclerotic lesions TG- and LDL-C-lowering and HDL-C-raising re-directs excess cholesterol from the peripheral tissues to the liver for excretion into the bile via HDL-C slowed progression of atherosclerosis Fatty acids, eico-sanoids (fatty acids derived from FAS ) Fibrates fenofibrate (Tricor ), genfibrozil (Lopid ) Dyslipidemia... [Pg.945]

While the fibric acid derivatives have antihyperlipidemic effects, their use varies depending on the drug. For example, Clofibrate (Atromid-S) and gemfibrozil (Lopid) are used to treat individuals with very high serum triglyceride levels who present a risk of abdominal pain and pancreatitis and who do not experience a response to diet modifications. Clofibrate is not used for the treatment of other types of hyperlipidemia and is not thought to be effective for prevention of coronary heart disease. Fenofibrate (Tricor) is used as adjunctive treatment for the reduction of LDL, total cholesterol, and triglycerides in patients with hyperlipidemia. [Pg.411]

The primary care provider prescribes fenofibrate (Tricor) for the treatment of hypertriglyceridemia. The patient is now taking 200 mg/d PO. Is this an appropriate dosage If not, what action would you take If the dose is appropriate, how many capsules would you administer if the drugis available in 54-mg capsules ... [Pg.416]

C7H4CI2O 122-01-0) see Acemetacin Benoxaprofen Bezafibrate Feclobuzone Fenofibrate Indometacin Moclobemide Progabide Rebamipide Zomepirac (2-chlorobenzoyi)cyciopentane (C12H13CIO 6740-85-8) see Ketamine... [Pg.2324]

Diclofenac, fenofibrate, lovastatin, methyldopa, minocycline, nitrofurantoin, phenytoin, and propylthiouracil... [Pg.117]

Chloral hydrate Chloramphenicol Cimetidine Ciprofloxacin Clofibrate Danazol Disulfiram Doxycycline Erythromycin Fenofibrate Fluconazole Fluorouracil Fluoxetine Fluvoxamine Gemfibrozil Influenza vaccine Isoniazid Itraconazole Fovastatin Metronidazole Miconazole Moxalactam Neomycin Norfloxacin Ofloxacin Omeprazole Phenylbutazone Piroxicam Propafenone Propoyxphene Quinidine Sertraline Sulfamethoxazole Sulfinpyrazone Tamoxifen Testosterone Vitamin E Zafirlukast... [Pg.153]

Fenofibrate 54, 1 60 mg tablets 54-1 60 mg/day Most common side effects are nausea, diarrhea,... [Pg.187]

EFV or NVP—THDL, NNRTI less than Pis annually micronized fenofibrate... [Pg.1272]

Koh KK, Quon MJ, Han SH, et al. Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia. J Am Coll Cardiol 2005 45(10) 1649-1653. [Pg.232]

The lipid regulator drugs bezafibrate and fenofibrate at initial concentrations of 4.5 and 4.2 ng g-1 in sterile sludge were completely removed after the fungal treatment. The fate of fenofibrate, also present in non-sterile sludge, was the same. Meanwhile, the most abundant atorvastatin, a cholesterol lowering statin, decreased its concentration in 80% and 65% in sterile and non-sterile conditions, respectively. [Pg.150]

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