Lipid metabolism pathways

Rapoport S. I. (2005). In vivo approaches and rationale for quantifying kinetics and imaging brain lipid metabolic pathways. Prostaglandins Other Lipid Mediat. 77 185-196. 

In addition to being incorporated into tissue proteins, amino acids, after losing their nitrogen atoms by deamination and/or transamination, may be catabolized to yield energy or to form glucose. Conversely, the nonessential amino acids may be synthesized from carbohydrate metabolism intermediates and ammonia or from essential amino acids. This section is devoted to the mechanisms of such metabolic processes and their interrelationships with carbohydrate and lipid metabolic pathways. 

D DIGE DEHP Mouse liver 59 protein IDs lipid metabolism pathway, and others altered by DEHP... 

In conclusion, fibrates exert their lipid-lowering effects through activation of a broad range of lipid metabolism pathways. Some of these could be selectively targeted by future drugs. 

Some of the LP kinase and lyase mutant mice have also been reported and their phenotypes are consistent with receptor mutant mice (Escalante-Alcalde et al., 2003 Schmahl et al., 2007). However, a number of enzymes are involved in lipid metabolic pathways so the existence of functional redundancy is therefore conceivable. Ongoing multiple and conditional gene targeting studies are helping to elucidate these pathways. 

ER plays an important role in the pathogenesis Ap is formed by y-secretase complex presenilin 1 (PS-1) and PS-2, which is located at the interface between mitochondria and ER. These organelles are in close contact, influenced by close lipid metabolic pathways, and therefore this environment is shown as a new potential determinant of AD pathogenesis [58]. 

One of the most promising tools for the dissection of lipid metabolic pathways is RNA interference. This rapidly emerging technology takes advantage of the... 

RECOGNITION OF LIPID METABOLISM PATHWAYS FOR DATA INTERPRETATION... 

Fig. 5. Gene Regulatory Network constructed using Cytoscape for visualizing the interconnection of the Lipid Metabolic Pathways restricted to L. major. ...

From the Cytoscape Regulatory Network of the Lipid Metabolism Pathway, it is found that the maximum number of the genes and the resultant gene products (enzymes), distinctive to the L major, ae specifically clustered in the LPG and GIPL Biosynthesis Pathway, followed by the fatty acid metabolism. 

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