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Linkage studies

TABLE S.8(o) Record-linkage Studies among Workers in the Printing Industry (lARC, 1996)... [Pg.243]

Extensive linkage studies Large families with defined pedigrees are desirable. Dominant genes are easier to recognize than recessives. [Pg.635]

Kruglyak L. The use of a genetic map of biallelic markers in linkage studies. Nature Genet 1997 17 21-24. [Pg.231]

The second type of investigation is the linkage study or genome scan in which there is no predetermined biological hypothesis for the genetic basis of the phenotype. This type of study measures the degree to which the trait is linked to markers which are placed randomly across the whole genome. These studies are discussed further in Section 22.3. [Pg.445]

Biallelic or Multiallelic Markers for Linkage Studies 451 Genome Scans in the Future 452 Evidence for the Genomic Basis of Nicotine Addiction from Animal Models 452... [Pg.577]

The concordance rate of mood disorders is 60-80% for monozygotic twins and 14-20% for dizygotic twins. Linkage studies suggest that certain loci on genes and the X chromosome may contribute to genetic susceptibility of bipolar disorder,... [Pg.771]

Stergachis A. Record linkage studies for post-marketing surveillance data quahty and vahdity considerations. Drugintell Clin Pharm 1988 22 157. [Pg.450]

Crowe RR, Noyes R Jr, Persico AM (1987a) Pro-opiomelanocortin (POMC) gene excluded as a cause of panic disorder in a large family. J Affect Disord 12 23-27 Crowe RR, Noyes R Jr, Wilson AF, Elston RC, Ward LJ (1987b) A linkage study of panic disorder. Arch Gen Psychiatry 44 933-937... [Pg.172]

Blum, K., Sheridan, P.J., Wood, R.C., Braverman, E.R., Chen, T.J., and Comings, D.E. (1995) Dopamine D2 receptor gene variants association and linkage studies in impulsive addictive-compulsive behavior. Pharmacogenetics 5 121-141. [Pg.234]

Vallada H, Craddock N, Vasques L, et al. Linkage studies in bipolar affective disorder with markers on chromosome 21. J Affect Disord 1996 41 217-221. [Pg.221]

Berrettini WH, Ferraro TN, Goldin LR, et al. A linkage study of bipolar illness. Arch Gen Psychiatry 1997 54 27-35. [Pg.221]

Blum, Kenneth, Peter J. Sheridan, R. C Wood, Eric R. Braverman, T. J. Chen, and David E. Comings. 1995. "Dopamine D2 Receptor Gene Variants Association and Linkage Studies in Impulsive-Addictive-Compulsive Behaviour." Pharmacogenetics 5 121-41. [Pg.93]


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See also in sourсe #XX -- [ Pg.445 ]




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