Linear assembly

DNA sequence The linear assembly of nucleotides along a DNA strand. 

As an example of linear assembly one can cite the dianion [Mo3( -S)4(CO)8]2, the molecular structure of which is shown in Figure 4.7... 

Many of the polycyclic antibiotics are based on linear assemblies of three or more six-membered rings, such as the tetracycline and anthracycline antibiotics (examples are chlortetracycline and... 

Fig. 7 Synthesis of pyridinium-based cationic lipids by a linear assembly strategy...

Fig. 10 Solid-phase synthesis of cationic lipids using submonomer (a) [147, 148] and monomer (b) [151, 152] linear assembly...

The linear assembly of glycosylated amino acids in particular usually provides well-defined products following this approach, the required carbohydrate structure is attached to an amino acid residue, typically serine and threonine for O-linked glycopeptides and asparagine for N-linked glycopeptides (Fig. I).16... 

In addition, by measuring the intensity fluctuations at low scattering angles changes in the translational diffusion coefficient can be measured during the early phases of self-assembly as illustrated by Figure 5.5. The translational diffusion coefficient decreases as the ratio of the length to width increases as linear assembly occurs. 

Gibson et al. recently demonstrated that a pseudorotaxane-like linear assembly can be synthesized from a bis crown ether moiety and a bis ammonium salt... 

From these examples it is clear that nature also provides convergent alternatives to the linear assembly of deoxysaccharides, as was, for example, observed in tylosin [90] or streptomycin (24) biosynthesis [72], A linear strategy is certainly also true for other aminoglycosides, although in the case of neomycin biosynthesis, an alternative disaccharyl transfer has been discussed [70],... 

A powdered mixture of lb and 2 in a 1 1 ratio was ground in a mortar with a pestle in the ambient atmosphere. The mixture became gummy immediately. After 10 min, the H NMR spectrum of the mixture in D20 exhibited complete consumption of the starting materials and formation of 3 b together with a small amount of other species that could be attributed to linearly assembled oligomers. Reprecipitation of the mixture from water-ethanol furnished a 76% yield of 3 b whose spectral data were fully consistent with that reported. 

While nucleic acids and proteins are linear assemblies, carbohydrates are structurally and stereochemically more diverse. A wide array of available... 

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