Lindane lotion 1%, shampoo

Lindane, a chlorinated hydrocarbon insecticide with scabi-cidal and pedicuhcidal properties (1% cream, lotion, shampoo), is used in scabies and pediculosis. 

Lindane (Kwell, etc) is available as a shampoo or lotion. For pediculosis capitis or pubis, 30 mL of shampoo is applied to dry hair on the scalp or genital area for 4 minutes and then rinsed off. No additional application is indicated unless living lice are present 1 week after treatment. Then reapplication may be required. 

Lindane (Kwell, etc) is available as a shampoo or lotion. For pediculosis capitis or pubis, one application of 30 mL of shampoo is worked into a lather and left on the scalp or genital area for 5 minutes and then rinsed off. No additional application is indicated unless living lice are present 1 week after treatment. Then reapplication may be required. Recent concerns about the toxicity of lindane have altered treatment guidelines for its use in scabies the current recommendation calls for a single application to the entire body from the neck down, left on for 8-12 hours, and then washed off. Patients should be retreated only if active mites can be demonstrated, and never within 1 week of initial treatment. 

Lindane in 1) cream, lotion and shampoo formulations is also used as a parasiticide and ovacide (Kwell) in the treatment of lice (ref. 92, p. 1446). Lindane has a local irritant action and can be absorbed dermally. Acute toxicity in humans may occur by all exposure routes ingestion, inhalation or dermal (ref. 97). All isomers of BHC act on the central nervous system (CNS), but not identically the gamma and... 

A Lindane formulation (mixture of BHC isomers) is used as a termiticide. The 1% shampoo,lotion or cream (Kwell) is also used as an ovacide. The isomer is a CNS stimulant of high acute toxicity, and caused serious illness including convulsions in a patient when administered as a vermifuge. Applications of lindane preparations have resulted in seizures in young children. 

HCH is still used in ointments, lotions, and shampoos to treat head and body lice and scabies. Lindane has not been produced in the United States since 1977. It is still imported and formulated in the United States, although its use is restricted by the USEPA and it can be applied only by a certified applicator. Technical-grade HCH is a mixture of several isomers of HCH. It also was used as an insecticide in the United States, but production stopped in 1983.12,14,48... 

Lindane is u.sed ItKally as a cream, lotion, or shampoo For the treatment of scabies and pediculosis. 

Lindane exerts its action by being directly absorbed into the parasite and ova. Lotion nsed in treatment of Sarcoptes scabiei (scabies) in patients who have failed to respond to adeqnate doses or are intolerant of other approved therapies. Shampoo used in treatment of Pediculus capitis (head lice) and Pediculus pubis (crab hce) and their ova in patients who have failed to respond to adequate doses or are intolerant of other approved therapies. 

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