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Receptor-ligand recognition

Fig. 3.3. Diagramatic Sketch of Complimentarity in Ligand Receptor Recognition (a) Illustrating shape complimentarity (b) Depicting electrostatic complimentarity (c) Showing hydrogen-bonding complimentarity. Fig. 3.3. Diagramatic Sketch of Complimentarity in Ligand Receptor Recognition (a) Illustrating shape complimentarity (b) Depicting electrostatic complimentarity (c) Showing hydrogen-bonding complimentarity.
Salient Features The various salient features with respect to the ligand-receptor recognition... [Pg.68]

Components of bonding affinity (n) Simulations and the thermodynamic cycle (/n) Ligand-receptor recognition. [Pg.102]

The function of multivalent ligands depends on the mechanism of action by which they operate. An understanding of the contributions that individual mechanisms can make to multivalent ligand-receptor recognition is required to effectively design more potent and selective multivalent inhibitors or effectors. [Pg.90]

If the aim of a 3D-QSAR analysis is to quantitate the features of ligand-receptor recognition, the biological data should reflect the affinity of the ligand for its receptor without being complicated by distribution to the site or metabolism. Because QSAR models are based on the differences in bioactivities of the compounds, there must be adequate variance in bioactivity within the data set. Additionally, 3D-QSAR should exceed in precision that of the bioactivity measurements. [Pg.186]

Characterization of the GABAa Receptor Recognition Site Through Ligand Design and Pharmacophore Modeling... [Pg.113]

See other pages where Receptor-ligand recognition is mentioned: [Pg.352]    [Pg.120]    [Pg.377]    [Pg.80]    [Pg.270]    [Pg.449]    [Pg.90]    [Pg.287]    [Pg.52]    [Pg.544]    [Pg.68]    [Pg.101]    [Pg.287]    [Pg.193]    [Pg.69]    [Pg.795]    [Pg.476]    [Pg.352]    [Pg.120]    [Pg.377]    [Pg.80]    [Pg.270]    [Pg.449]    [Pg.90]    [Pg.287]    [Pg.52]    [Pg.544]    [Pg.68]    [Pg.101]    [Pg.287]    [Pg.193]    [Pg.69]    [Pg.795]    [Pg.476]    [Pg.39]    [Pg.184]    [Pg.165]    [Pg.169]    [Pg.435]    [Pg.40]    [Pg.177]    [Pg.181]    [Pg.207]    [Pg.214]    [Pg.465]    [Pg.113]    [Pg.186]    [Pg.375]    [Pg.139]    [Pg.157]    [Pg.161]    [Pg.166]    [Pg.108]    [Pg.88]    [Pg.224]    [Pg.274]    [Pg.311]    [Pg.163]    [Pg.164]    [Pg.177]   
See also in sourсe #XX -- [ Pg.90 ]

See also in sourсe #XX -- [ Pg.68 ]



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