Lead compound production structure-based drug design

We presented a review of the natural product chemistry found in species of Pseudopterogorgia. These metabolites function as predator deterents and some of them proved to be (potential) therapeutic agents. The discovery of pseudopterosins and their potent anti-inflammatory activity should be especially highlighted as one of the most prominent (marine chemistry) scientific inventions of the last decade. We feel that the combination of the discoveries reviewed herein combined with drug design based on structure activity studies of these compounds will lead to therapeutic agents which although derived from marine life chemistry, will not rely on it as a source. 

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