L-Cyclohexyl-5-methyl

NC — CHa — COOR] Imidazol-3-oxid l-Cyclohexyl-5-(hydroximino-methyl)- E8c, 23 (HO-N=CH-CO-CH=N-OH + CH20/HnC6-NH2) Malonsaure... 

Imidazol 5-Amino-4-aminocarbonyl-l-cyclohexyl-2-methyl- E8c, 57 [H2N-CO-CH(CN)-N = C(CH3)-OC2H5 + HMC6-NH2]... 

The reaction between 5-methyl-2-(l-methyl-1 -phenylethyl)cyclohexyl 2-oxoacetate and 2-buteny](tributyl)stannane promoted by boron trifluoride-diethyl ether complex showed a strong preference for 57-facial attack, with syn selectivity69. 

An efficient synthesis of optically active pentanedioates is possible using ester enolates based on chiral alcohols. This is illustrated by the addition of the lithium (fl-cnolate of (1 R,2S,5R)-5-methyl-2-(1-methyl-l-phenylethyl)cyclohexyl propanedioate to methyl ( )-2-butenoate at — 100 °C which shows simple and induced diastereoselectivity. 

Methyl l-((l/f,25,5/ )-5-Methyl-2-(l-methyl-l-phenyleth l)cyclohexyl Propanedioate (1) Typical Procedure186 ... 

The uracils with herbicidal activity do not necessarily contain 5-halo substituents. 3-Cyclohexyl-5-methyluracil [354] (XLIV), l,3-di-isopropyl-6-methyl-uracil [352] (XLV) and 3-s-butyl-5-thiocyanato-6-methyluracil [353] (XLVI), for example, are cited as having this type of activity. 3-Butyl-6-methyluracil (XLlllc) possesses interesting selective activities. For instance, this pyrimidine kills many annual weed species without damage to peas and peanuts, even when applied at twice the concentration needed to kill the weeds [346]. On the other hand, the related 5-bromo derivatives, such as (XLlIlb), are useful as industrial herbicides where it is desirable to kill all plants [346]. 

Acetic acid, chloro-, 5-methyl-2-(l-methyl-l-phenylethyl)cyclohexyl ester, [lR-(la,28,5a)]-, 65, 203... 

Methyl-2-(l-methyl-1-phenylethyl)cyclohexanone, (2S.5R)- Cyclohexanone, 5-methyl-2-(l-methyl-l-phenylethyl-, (2S-cis)- (65337-06-6), 65, 203 5-Methyl-2-(l-methyl-l-phenylethyl)cyclohexyl chloroacetate, (1R,2S,5R)- Acetic acid, chloro-, 5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester, [lR-(la,Z0,5a)]- (71804-27-8), 65, 203 5-Methyl-2-[l-methyl-l-(phenylmethylthio)ethyl]cyclohexanone, cis- and trans 65, 215... 

Dodge, J. A. Nissen, J. S. Presnell, M. A general procedure for Mitsunobu inversion of sterically hindered alcohols inversion of menthol. (lS,2S,5R)-5-Methyl-2-(l-methyl-ethyl) cyclohexyl 4-nitrobenzoate. Org. Synth. 1998, Coll. Vol. IX, 607-609. 

A mixture of 5-oxo-3-methyl-5-cyclohexylpentene-2 acid 1-methyl ester and 5-oxo-3-methyl-5-cyclohexylpentene-3 acid 1-methyl ester was obtained by condensation of hexahydrobenzoyl chloride with p,p-dimethylacrylic acid methyl ester. 11.2 g of this mixture and a solution of 4.6 g of sodium acetate and 4 g of hydroxylamine hydrochloride were shaken for 20 hours at 25°C with a mixture of 8 ml of water and 15 ml methanol. Subsequently, a solution of 4 g of sodium hydroxide in 8 ml of water was then added, while cooling, shaken for 1 hour at room temperature. The mixture was extracted by means of benzene and the aqueous phase was acidified to reach a pH of 6. 3.5 g of l-hydroxy-4-methyl-6-cyclohexyl-2-pyridone were obtained melting point 144°C. 

CN a-cyclohexyl-a-hydroxybenzeneaceticacid (l,4,5,6-tetrahydro-l-methyl-2-pyrimidinyl)mcthyl ester... 

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