L-2-Aminopropanoic Acid

Aminopeptidase, Leucine (Aspergillus nigerwea., Aspergillus oryzae var., and other microbial species), (S3)19 DL-a-Amino-(3-phenylpropionic Acid, 292 L-a-Amino-P-phenylpropionic Acid, 292 DL-2-Aminopropanoic Acid, 18 L-2-Aminopropanoic Acid, 18 L-a-Aminosuccinamic Acid, 35 DL-Aminosuccinic Acid, 36, (S3)7 L-Aminosuccinic Acid, 37, (S2)l, (S3)7 Ammonia-Ammonium Chloride Buffer TS, 850... 

After deprotonation of (V-methoxycarbonylmethyldiphenylmethanimine with lithium diiso-propylamide in THF, the a-methylation with various mixed sulfates leads after acidification to (S)-2-aminopropanoic acid (L-alanine) in a yield of 40 60% and an ee as high as 40% 13 14. 

Tabic 2. (S)-2-Aminopropanoic Acid [(L)-Alanine] by Alkylation of jV-Methoxycarbonylmethylmetha-nimines with Various x-(D)-Glucofuranose 3-Sulfates... 

SYNS ALANINE a-ALANINE l-(+)-ALANINE 1-a-ALANINE (S)-ALANINE 1-2-AMINO-PROPANOIC ACID (S)-2-AMINOPROPANOIC ACID a-AMINOPROPIONIC ACID... 

L-a-aminopropionic acid (5>-2-aminopropanoic acid. C3-H7N02 mol wt 89.09. C 40.44%, H 7.92%, N 15,72%, O 35,92%. CH3CH(NH2)COOH, An amino acid classified as non-essential for the maintenance of growth in rats. Obtained from proteins. Prepn of i>L-form Zelinsky, Stadni-koft Ber. 41, 2061 (1908) Benedict, J. Am. Chem. Soc. 51, 2277 (1929) Cocker. Lapwroth, J. Cham. Soc. 1931, 1399 Kendall, McKenzie, Org. Syn. ColL Vol, I (2nd Ed., 1941) p 21. Laboratory procedure making use of acid hydrolysis of silk fibroin (degummed white silk) Stein et al. J. Biol... 

CAS 56-41-7 EINECS/ELINCS 200-273-8 Synonyms Alanine (INCI) a-Alanine L-a-Alanine 1,2-Aminopropanoic acid 2-Aminopropionic acid... 

CAS 52-90-4 EINECS/ELINCS 200-158-2 FEMA 3263 INS920 E920 Synonyms L-2-Amino-3-mercaptopropanoic acid (+)-2-Amino-3-mercaptopropionic acid a-Amino-P-thiopropionic acid L-2-Amino-3-thiopropionic acid Cystein Cysteine (INCI) 3,3 -Dithiobis (2-aminopropanoic acid) P-Mercaptoalanine L-P-Mercaptoalanine Tioserine Classification A nonessential amino acid Empirical C3H7NO2S Formula HSCH2CH(NH2)COOH Properties Colorless cryst. sol. in water, ammonium hydroxide, acetic acid insol. in ether, acetone, benzene, carbon disulfide, CCU m.w. 121.16 m.p. 220 C (dec.)... 

Dibenzamidodiphenyl disulfide 2,2 -Dithiobisacetic acid, diammonium salt. See Diammonium dithiodiglycolate p,P -Dithiobisalanine. See L-Cystine 3,3 -Dithiobis (2-aminopropanoic acid). See L-Cysteine... 

One group of compounds that exhibit optical isomerism is the Z-amino acids that are used in cells to synthesize proteins. Of the 20 amino acids utilized for this purpose, all but glycine (Z-aminoethanoic acid) are chiral molecules. It is interesting to realize that it is the L-form of all these amino acids that is exclusively used by the protein-synthesizing machinery of the cell. Alanine (2-aminopropanoic acid) illustrates the optical isomerism shown by the 2-amino acids (Figure 20.70). 

A handbook that lists only pfCg values for weak electrolytes has the following entry for 1,2-ethanediamine, NH2CH2CH2NH2 p/aminopropanoic acid, NH2CH(CH3)C00H pKi = 2.34(-l-1) p/<2 = 9.87(0). Interpret these handbook entries by writing equations for the ionization reactions to which these pfC values apply. What are the corresponding values of the base ionization constants Kb, and Kbj ... 

Before analyzing in detail the conformational behaviour of y9-peptides, it is instructive to look back into the origins and the context of this discovery. The possi-bihty that a peptide chain consisting exclusively of y9-amino acid residues may adopt a defined secondary structure was raised in a long series of studies which began some 40 years ago, on y9-amino acid homopolymers (nylon-3 type polymers), such as poly(/9-alanine) 3 [14, 15], poly(y9-aminobutanoic acid) 4 [16-18], poly(a-dialkyl-/9-aminopropanoic acid) 5 ]19], poly(y9-L-aspartic acid) 6 ]20, 21], and poly-(a-alkyl-/9-L-aspartate) 7 [22-36] (Fig. 2.1). 

One oxidative method used an aromatic ring as a carboxyl surrogate. Oxidation of 1.205 with ruthenium oxide, for example, gave 4-aminobutanoic acid (J.2).H9 Similar oxidation of tyramine gave an 86% yield of 3-aminopropanoic acid (i.l). 

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