4- -L-alanin

H3C-CH-COOH OH (D.L) h3c-co-cooh K.ontinuierlicher Multi-enzym-Reaktor NADfNADH auf Polyethenylen-glykol -4 L-Alanin a a 1... 

Figure 4 L-Alanine scan of NPY. Affinity of the peptide at (a) SK-N-MC cells (Y1 receptor) and (b) SMS-KAN cells (Y2 receptor) is shown.

Alanine, ( )- -(2-amino-1,3-selenazol-4-yl)-synthesis, 6, 343 Alanine, phenyl-p-hydroxylation, 7, 565 Alanine, selenienyl-synthesis, 4, 964 Alanine, y3-2-selenienyl-applications, 4, 970 Alanine, y3-3-selenienyl-applications, 4, 970 Alanine, y3-2-thienyl-biological activity, 4, 911 Alanine, -3-thienyl-biological activity, 4, 912 L-Alanine, y-L-glutamyl-y3-pyrazolyl-occurrence, 5, 303 L-Alanine, -pyrazolyl-occurrence, 5, 303 Alanine raeemase inhibition, 1, 266 Albendazole... 

Figure A8.14 Closed column reactor for the production of L-alanine. 1) reactor 2) plunger pump 3) pressure control valve 4) reservoir 5) substrate tank 6) pressure gauge 7) safety valve 8) heat exchanger.

Although useful, this synthesis of reduced quinoxalines has not been fully developed yet. 7-Azabicyclo[4.1.0]heptane (423, R = H) and glycine (424, Q = H) in refluxing aqueous ammonium chloride for 90 min gave octahydro-2(l//)-quinoxalinone (425, Q = R = H) in 40% yield." Similar treatment of 7-methyl-7-azabicyclo[4.1.0]heptane (423, R = Me) gave l-methyloctahydro-2(l//)-quinox-alinone (425, Q = H, R = Me) in 62% yield and 7-methyl-7-azabicyclo[4.1.0] heptane (423, R = Me) with L-alanine (424, R = Me) in refluxing aqueous ammonium chloride for 16 h gave two separable diastereoisomers of 1,3-dimethylocta-hydro-2(l//)-quinoxalinone (425, Q = R = Me), isolated as hydrochlorides in 26%... 

Treatment of N-benzoyl-L-alanine with oxalyl chloride, followed by methanolic triethylamine, yields methyl 4-methyl-2-phenyloxazole-5-carboxylate 32 <95CC2335>. a-Keto imidoyl chlorides, obtained from acyl chlorides and ethyl isocyanoacetate, cyclise to 5-ethoxyoxazoles by the action of triethylamine (e.g.. Scheme 8) <96SC1149>. The azetidinone 33 is converted into the oxazole 34 when heated with sodium azide and titanium chloride in acetonitrile <95JHC1409>. Another unusual reaction is the cyclisation of compound 35 to the oxazole 36 on sequential treatment with trifluoroacetic anhydride and methanol <95JFC(75)221>. 

Amino acid abbreviations aa, generic amino acid Ala, L-alanine Aib, 2-aminoisobutyric acid Cys, L-cysteine Asp, L-aspartic acid Glu, L-glutamic acid Gly, glycine Lys, L-ly-sine Ser, L-serine Trp, L-tryptophan Ser, 2-amino-3-(5-methyl-2,4-dioxo-3,4-dihydro-2H-... 

Fumaric acid to L-aspartic acid, L-aspartic acid to L-alanine Enzymatic resolution of methyl ester of (+/-) trans 4- methoxy-... 

A simple and rapid method of separating optical isomers of amino acids on a reversed-phase plate, without using impregnated plates or a chiral mobile phase, was described by Nagata et al. [27]. Amino acids were derivatized with /-fluoro-2,4-dinitrophenyl-5-L-alanine amide (FDAA or Marfey s reagent). Each FDAA amino acid can be separated from the others by two-dimensional elution. Separation of L- and D-serine was achieved with 30% of acetonitrile solvent. The enantiomers of threonine, proline, and alanine were separated with 35% of acetonitrile solvent and those of methionine, valine, phenylalanine, and leucine with 40% of acetonitrile solvent. The spots were scraped off the plate after the... 

N-[N-(benzyloxycarbonyl)-L-aspart-l-oyl-(L-alanyl-L-threonyl-L-leucyl-L-alanine p-nitrobenzyl ester)-4-oyl]-N-[N-(benzyloxycarbonyl)-L-aspart-l-oyl-(L-alanyl-L-threonyl-L-leucyl-L-alanyl-L-serine p-nitrobenzyl ester)-4-oyl]-N-[N-(benzyloxycarbonyl)-L-aspart-1 -oyl-(glycine ethyl ester)-4-oyl -N-[N-(benzyloxycarbonyl)-L-aspart-l-oyl-(glycyl-L-serine methyl ester)-4-oyl]-... 

N-[N-(benzyloxycarbonyI)-L-prolyl-L-aspart-4-oyl]-N-[N-(benzyloxycarbonyl)-L-seryl-L-aspart-l-oyl-(L-alanine methyl ester)-4-oyl]-... 

L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophanyl-L-lysyl-L-threonyl-L-threonyl-L-cysteine 6-0-benzoyl-N-(benzyloxycarbonyl) methylamide 4,6-0-benzylidene-N-benzylidene-N-(benzyloxycarbonyl) methylamide N- (benzyloxy carbonyl) -N-(benzyloxycarbonyl)-, amide N-(benzyloxycarbonyl)-, hydrazide N-(benzyloxycarbonyl)-, methylamide N-(benzyloxycarbonyl)-, methyl ester N-(benzyloxycarbonyl)-L-alanyl-L-alanine methyl ester N-(benzyloxycarbonyl)-L-alanylglycine ethyl ester N-(benzyloxycarbonyl)glycyl-L-alanine methyl ester 3,4,6-tri-0-acetyl-2-amino-2-deoxy-N-(benzyloxycarbonyl)-, benzyl ester, hydrochloride... 

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