Amino acid abbreviations

Amino acid abbreviations aa, generic amino acid Ala, L-alanine Aib, 2-aminoisobutyric acid Cys, L-cysteine Asp, L-aspartic acid Glu, L-glutamic acid Gly, glycine Lys, L-ly-sine Ser, L-serine Trp, L-tryptophan Ser, 2-amino-3-(5-methyl-2,4-dioxo-3,4-dihydro-2H-... 

Standard one-letter amino acid abbreviation (see list of Abbreviations and Acronyms). 

A -acetylmuramic acid) residues. These chains are cross-linked via peptide structures. Part of the peptidoglycan of Staphylococcus aureus is shown here. Amino acid abbreviations are given in Chapter 13. 

Amino-acid abbreviations are spelled out in Appendix V. Through a series of structure-activity relationship studies, the bioactive conformation and peptide sequences that produce undesirable biologic responses were identihed. Also identified were sequences susceptible to proteolysis, and a working-model compound that eliminated these sequences was proposed (Figure 4.6). This allowed the rational design of optimized somatostatin analogues with desirable biologic characteristics and activity and increased stability. 

Amino acid abbreviations are the standard one- and three-letter ones... 

Amino acid Abbreviation Structure Common name of side chain Md Pi... 

Figure 16.22 Structure of bovine brain calmodulin. See Chapter 4 for amino acid abbreviations. (Reproduced by permission from Klee CB, Crouch TH, Richman PG. Calmodulin. Annu Rev Biochem 49 489-515, 1980.)...

Three-letter amino acid abbreviations maybe preceded by a configurational designator, d or l, set in small capital letters. 

Amino acid Abbreviation B. mori Fibroin Sericin F. c. nctm Fibroin M clavipes Draghne... 

Amino Acid Abbreviation Side Chain pKg Abundance Sequence" Modify With ... 

Tryptic peptide sequences are indicated in the figure. lUPAC nomenclature is used for amino acid abbreviation. 

Tryptic peptide sequences are indicated in the figure above the predicted sequence. A lower case a, b, or c following the peptide designation indicates that the peptide was obtained as a mixture of peptides. lUPAC nomenclature is used for amino acid abbreviation. 

Figure 2-4. Structures of the amino acids. Abbreviations are given for all amino acids. (A) shows amino acids that do not have ionizable side chains. (8) shows side chains that are ionizable. In 8, for each amino acid, the species that predominates at a pH below the pK is shown on the left, the species that predominates at a pH above the pK is shown on the right (8). Note that the charge changes from 0 to - or from + to 0. At the pK, equal amounts of both species are present.

Amino acid abbreviations (found in literature related and unnatural)... 

Appendix B comprises three tables amino acid abbreviations (common natural), amino acid abbreviations (found in literature - related and unnatural) and Greek and Latin multiplicative prefixes. 

Amino Acid Abbreviation PKal PKa2 PKR Isoelectric Point pi (Ethanol —> Water) kj/mol... 

UUU Codon (nucleotide triplet) I Phe I Amino acid abbreviation)... 

Full name of mycosporine-like amino acid Abbreviation (nm) (dm mole cm ) Species Reference m 9... 

Dire consequences may result if one or more of these amino acids is either absent or overabundant. For instance, a genetic disorder called phenylketonuria (PKU) is caused by the body s inability to get rid of extra phenylalanine, an amino acid abbreviated Phe. PKU is an autosomal recessive disorder, meaning that the only way to get the disease is if both of your parents carry a version of a gene linked with this disease. If only one parent has the gene linked to PKU, his or her children cannot develop the disease. Children who have... 

V-M-Y-Y-E-N This is the single-letter amino acid abbreviation for a peptide. Draw the structure of this peptide. What is the net charge of this peptide at pH 7.0 An enzyme called a protein tyrosine kinase can attach phosphates to the hydroxyl groups of tyrosine. What is the net charge of the peptide at pH 7.0 after it has been phosphorylated by a tyrosine kinase What is the likely source of phosphate utilized by the kinase for this reaction ... 

Single-letter amino acid abbreviations used for sequences (see Figure 2-13). X 0 = hydrophobic residue. Brackets enclose alternative permissible residues. 

X = any amino acid <1) = hydrophobic amino acid. Single-letter amino acid abbreviations are in parentheses. 

Amino acid Abbreviation/ symbol Mr pKi (-C00H) pKi (-NHn pKr (R group) pi Hydropathy index Occurrence in proteins (%) ... 

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