Krukenberg tumor

Lerwill ME, Young RH. Ovarian metastases of intestinal-type gastric carcinoma A clinicopathologic study of 4 cases with contrasting features to those of the Krukenberg tumor. Am J Surg Pathol. 2006 30 1382-1388. 

McClu age WG, Young RH. Primary ovarian mucinous tumors with signet ring cells Report of 3 cases with discussion of so-called primary Krukenberg tumor. Am J Surg Pathol. 2008 32 1373-1379. 

Kiyokawa T, Young RH, Scully RE. Krukenberg tumors of the ovary A clinicopathologic analysis of 120 cases with emphasis on their variable pathologic manifestations. Am J Surg Pathol. 2006 30 277-299. 

The physical examination in patients with gastric adenocarcinoma is nsnally normal. In advanced disease, a palpable abdominal mass, hepatomegaly, or ascites may be present. Lymph nodes may be palpated at the umbilicns (Sister Mary Joseph s node) or the supraclavicular region (Virchow s node). A perirectal mass may occur, with tumor deposition in the rectal pouch (Blumer s shelf), and palpable ovarian enlargement may occur with tumor seeding as well (Krukenberg tumor). 

Sclerosing stromal cell tumors seem to have a unique distinct centripetal contrast media uptake. Morphologically, they may resemble Krukenberg tumors or dysgerminomas. 

Fig. 10.2. Necrosis in Krukenberg tumor. Parasagittal contrast-enhanced Tl-weighted image shows a well-delineated solid ovarian lesion (arrow) located cephalad of the uterus. It displays inhomogeneous contrast enhancement and a large central necrosis...

Metastatic cancers different from Krukenberg tumors may have a variable appearance resembling other malignant ovarian lesions with cystic and mixed cystic and solid patterns [64,67]. 

Confident distinction between primary and metastatic ovarian cancers is not possible because of overlapping findings in imaging. Bilateral, sharply delineated, purely solid or predominantly solid tumors with necrosis strongly favor the diagnosis of a metastatic ovarian tumor, most likely Krukenberg tumors [68]. Contrast uptake aids in the differentiation of solid ovarian metastases from stromal tumors. Stromal tumors typically display a mild and delayed contrast uptake [69]. If metastases are cystic... 

Kim SH, Kim WH, Park KL et al (1996) CT and MR findings of Krukenberg tumors comparison with primary ovarian tumors. J Comput Assist Tomogr 20 393-398... 

Krukenberg s tumor spread to the ovary Diagnosis endoscopy and biopsy Treatment gastrectomy Prognosis poor overall -year survival 70%... 

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