Kornberg

Phosphoribosyl pyrophosphate synthetase (from human erythrocytes, or pigeon or chicken liver) [9015-83-2] Mr 60,000, [EC 2.7.6.1]. Purified 5100-fold by elution from DEAE-cellulose, fractionation with ammonium sulfate, filtration on Sepharose 4B and ultrafiltration. [Fox and Kelley J Biol Chem 246 5739 197h, Flaks Methods Enzymol6 158 1963 Kornberg et al. J Biol Chem 15 389 7955.]... 

In a sort of reciprocal arrangement, the cell also feeds many intermediates back into the TCA cycle from other reactions. Since such reactions replenish the TCA cycle intermediates, Hans Kornberg proposed that they be called anaplerotie reactions (literally, the filling up reactions). Thus, PEP carboxylase and pyruvate carboxylase synthesize oxaloacetate from pyruvate (Figure 20.24). 

Kornberg RD, Lorch Y (1999). Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome. Cell 98 285-294. 

Kornberg A Basic research The lifeline of medicine. FASEB J 1992 6 3143. 

Kornberg A Centenary of the birth of modern biochemistry. FASEB J 1997 11 1209. 

Values for ATP and most others taken from Krebs and Kornberg (1957). They differ between investigators depending on the precise conditions under which the measurements are made. 

Krebs HA, Kornberg HL Energy Transformations in Living Matter. Springer, 1957. 

Cramer P, Bushnell DA, Kornberg R Structural basis of transcription RNA polymerase II at 2.8 angstrom resolution. Science 2001 292 1863. 

Hayaishi O, A Kornberg (1952) Metabolism of cytosine, thymine, uracil and barbituric acid by bacterial enzymes. J Biol Chem 197 717-732. 

Honstead, J.E, Radionuclide burden-diet relationships near a nuclear facility, in Diagnosis and Treatment of Deposited Radionuclides, Kornberg, H.A. and Norwood, W.D., Eds., Excerpta Medica, Amsterdam, 1968. 

Popplewell, D.S., Boocock, G. In Diagnosis and Treatment of Deposited Radionuclides Proceedings of a Conference, Richland, Washington, edited by Kornberg, H.A., Norwood, W.D. Amsterdam Excerpta Medica Foundation 1967... 

Lia G, Praly E, Ferreira H, Stockdale C, Tse-Dinh YC, Dunlap D, Croquette V, Bensimon D, Owen-Hughes T (2006) Direct observation of DNA distortion by the RSC complex. Mol Cell 21 417 25 Lorch Y, Davis B, Kornberg RD (2005) Chromatin remodeling by DNA bending, not twisting. Proc Natl Acad Sci U S A 102 1329-1332 Luger K (2006) Dynamic nucleosomes. Chromosome Res 14 5-16... 

Kornberg, R.D. (1998) Cold Spring Harb. Symp. Quant. Biol. 63, 229-232. 

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