Knowledge integration into

Core Hazards were the base cells of knowledge integrated into the knowledge stmcture. In a way, the Risk universe was partitioned into galaxies of hazards. 

In any given situation, there may be different levels of dependence between an operator s performance on one task and on another because of the characteristics of the tasks theraseb e.s. or because of the manner in which the operator was cued to perform the tasks. Dependence levels between the performances of two (or more) operators also may differ. The analyses should account for dependency in human-error probabilities. In addition, each sequence may have a set of human recovery actions that if successfully performed will terminate or reduce the consequences of the sequence. This information, coupled with a knowledge of the system success criteria leads to the development of human success and failure probabilities which are input to the quantification of the fault iices or event trees. With this last step, the HRA is integrated into the PSA, and Pl. ise 4 is complete. 

In spite of the potential benefit, the possibilities of logistics simulation are often not fully exploited. Some reasons are a lack of knowledge about the basic metbod-ology and the available simulation tools, the fact that simulation models are rarely deployed more than once, and simulation investigations are often integrated into the planning process too late. 

It is true that in his own work De Donder did not pursue the consequences of nonequilibrium very far. We have to wait until the basic discovery of Onsager s reciprocity relations in 1931 and till the work of Eckart, Meixner, and many others in the 1940s and the 1950s to see thermodynamics of nonequilibrium processes take shape and be integrated into common knowledge. 

The second observation is that proper application and integration of interface and colloid science requires, besides factual knowledge. Insight into the many basic laws of physics and chemistry upon which it rests. 

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