Kidneys potassium retained/excreted

Aldosterone influences electrolyte balance in the body. Specifically, aldosterone increases the excretion of potassium by the kidney but decreases the excretion of sodium by this organ. One result is the net retention of water. The action of mineralocorticoids tends to increase blood pressure. Basically, the more sodium you retain, the more water you retain. Retaining water tends to increase the fluid level in the vascular system and that increases blood pressure. Think about the pressure changes that happen when you continue to fill a flexible container such as a balloon with water the more water, the greater the pressure in the balloon. You might well imagine that an... 

The kidneys excrete 80% of the daily potassium intake. Therefore when the kidney is unable to excrete potassium appropriately, as in acute renal failure and CKD, potassium is retained and often results in hyperkalemia. Moreover, many drugs can inhibit the kidney s ability to excrete potassium by inhibiting aldosterone and thus contribute to an increase in serum potassium levels. 

Fowler 1991). Insoluble species of tantalum, administered orally to rats, are poorly absorbed from the gastrointestinal tract, with total excretion accounted for in the feces. Ta administered orally to rats as soluble potassium tantalate was rapidly excreted almost exclusively via the fecal route less than 2% of the dose was retained after 1 day (Fleshman etal. 1971). More than 96% of the administered dose was excreted after 3 days, and less than 0.5% was recovered in urine after 7 days, although more than 97% of the total dose had been excreted. After absorption, Ta was primarily localized in the bone compartment, which retained over 40% of the total body burden after 14 days, and in the kidneys (Fleshman et al. 1971). The biological half life of the soluble, short-lived radionuclide (tj2 = 9.3 min) Ta given as Ta-chloride or Ta-oxide to dogs via intravenous administration was 190 min, with 78% of the Ta being found in the plasma ( 33% with the plasma protein fraction) and the remainder in red blood cells (Wilson etal. 1987). The distribution of soluble Ta administered intravenously to mice demonstrated Ta accumulation primarily in kidney (17% of the dose), followed by liver (9%) and blood (8.5%) (Wilson et al. 1987). 

Potassium concentration kidneys excrete more water and sodium — retain, potassium concentration ... 

A hormone produced in the adrenal gland, aldosterone, signals the kidneys to excrete or retain potassium based on the body s needs. If potassium levels are high, aldosterone is secreted, causing an increase in potassium excretion into the urine. Serum levels of potassium also are influenced by the levels of other electrolytes and acid-base balance. In alkalosis, for example, potassium may shift out of the cell as hydrogen ions shift into the cell to buffer the excessive acid, and when serum potassium concentration is low, potassium is retained by excreting sodium and chloride. 

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