Khosla

Benzyl 4-nitrophenyl carbonate [13795-24-9] M 273.2, m 78-80 . Dissolve in Et20, wash with H2O (3x) and satd aq NaCl, dry (MgS04), evap in vac and recryst residue from a small vol of MeOH, m 78-79°. Alternatively dissolve in Et20, wash with N HCI (2x), 0.5N NaHC03 (4x) then H2O, dry (Na2S04), evap Et20 and recryst residue from CgHg-pet ether, m 79-80°. [Khosla et al. Indian J Chem 5 279 7967 Wolman et al. J Chem Soc (C) 596 1 976.]... [Pg.129]

RIGGS B L, KHOSLA s and MELTON L J, 111 (1998) A Unitary model for involutional osteoporosis estrogen deficiency causes both type 1 and type 11 osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Min Res 13, 16 i-l i. [Pg.105]

Khosla, C. (1996) Combinatorial chemistry and biology an opportunity for engineers. Current Opinion in Biotechnology, 7, 219. [Pg.257]

Khosla, C. (1997) Harnessing the biosynthetic potential of modular polyketide synthases. Chemical Reviews, 97, 2577. [Pg.257]

Khosla, C. and Keasling, J.D. (2003) Metabolic engineering for drug discovery and development. Nature Reviews. Drug Discovery, 2, 1019. [Pg.257]

Kumar, P., Koppisch, A.T., Cane, D.E. and Khosla, C. (2003) Enhancing the modularity ofthe modular polyketide synthases transacylation in modular polyketide synthases catalyzed by malonyl-CoA ACPtransacylase. Journal of the American Chemical Society, 125, 14307. [Pg.258]

McDaniel, R., Licari, P. and Khosla, C. (2001) Process development and metabolic engineering for the overproduction of natural and unnatural polyketides in Metabolic Engineering, vol. 73 (ed. 1. Nielsen), Springer, Berlin, pp. 31-52. [Pg.282]

Khosla, C.Z.R. (1996) Generation of polyketide libraries via combinatorial biosynthesis. Trends in Biotechnology, 14, 335-341. [Pg.282]

Lu, H., Tsai, S.-C., Khosla, C. and Cane, D.E. (2002) Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase. Biochemistry, 41, 12590-12597. [Pg.316]

Doran PM, Riggs BL, Atkinson EJ, Khosla S (2001) Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. J Bone Miner Res 16 2118-2125... [Pg.141]

Khosla S (2001) Minireview the OPG/RANKL/RANK system. Endocrinology 142 5050-5055... [Pg.190]

Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Spelsberg TC, Riggs BL (1999) Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 140 4367-4370... [Pg.190]

Spelsberg TC, Subramaniam M, Riggs BL, Khosla S (1999) The actions and interactions of sex steroids and growth factors/cytokines on the skeleton. Mol Endocrinol 13 819— 828... [Pg.192]

Hofbauer LC, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S (1998) Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. BioChem Biophys Res Commun 250 776-781... [Pg.195]

Hofbauer LC, Shui C, Riggs BL, Dunstan CR, Spelsberg TC, O Brien T, Khosla S... [Pg.195]

Gupta AK, Khosla K (2007) Integration of soil solarization and potential native antagonist for the management of crown gall on cherry rootstock colt. Scientia Horticulturae 112 51-57. doi 10.1016/j.scienta.2006.12.004... [Pg.260]

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