Journal of Computer-Aided Molecular Design

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SeeDs screening hit rates for 12 protein targets. With kind permission from Springer Science+Business Media Journal of Computer-Aided Molecular Design, 23,2009,603, l-Jen Chen and Roderick E. Hubbard, Table 4... 

Fig. 11.4. Targets with observed high (>2%, light bars) and low (<2%, darker bars) Class 1 hit rates compared to the druggability score (Dscore) calculated by SiteMap. The red arrow indicates the minimum Dscore for targets yielding high hit rates for the current data set. With kind permission from Springer Science+Business Media Journal of Computer-Aided Molecular Design, 23, 2009, 603, l-Jen Chen and Roderick...

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Hindle, S.A., Rarey, M., Buning, C., Len-gauer, T. Flexible docking under pharmacophore constraints. Journal of Computer-Aided Molecular Design 2002, 16, 129-149. 

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