Journal of Combinatorial Chemistry

Lee, M.L. Schneider, G. (2001) Scaffold Architecture and Pharmacophoric Properties of Natural Products and Trade Drugs Application in the Design of Natural Product-Based Combinatorial Libraries. Journal of Combinatorial Chemistry, 3, 284-289. 

Schematic of a 64-electrode cell for electrochemical screening of electrocatalysts. (Reprinted with permission from Journal of Combinatorial Chemistry, 6,149 (2004). Copyright 2004 American Chemical Society.)...

Fang LL, Wan M, Pennacchio M, Pan JM. Evaluation of evaporative light-scattering detector for combinatorial library quantitation by reversed phase HPLC. Journal of Combinatorial Chemistry 2, 254-257, 2000. 

This paper describes the preparation of a number of libraries constructed with this reaction. A. V. Ivachtchenko, V. V. Kobak, A. P. Il yin, A. S. Trifilenkov, A. A. Busel, Journal of Combinatorial Chemistry 2003, 5, 645... 

A. Weissberg, A. Dahan, M. Portnoy, Journal of Combinatorial Chemistry 2001, 3, 154... 

The Journal of Combinatorial Chemistry recommends the use of ChemSet notation, in which a structure number is followed by the reagent sets associated with it. The structure number is typeset in bold, and the reagent sets are set in italics and enclosed in curly brackets. 

A convenient descriptive notation for combinatorial libraries (recommended by the Journal of Combinatorial Chemistry) is the ChemSet terminology. 

Arya, P., Wei, C.-Q., Barnes, M. L., Daroszewska, M. (2004) A solid phase library synthesis of hydroxyindoline-derived tricyclic derivatives by Mitsrmobu approach. Journal of Combinatorial Chemistry, 6, 65—72. 

Solution- and solid-phase, modular approaches for obtaining different natural product-hke polycyclic architectures from an aminoindoline scaffold for combinatorial chemistry. Journal of Combinatorial Chemistry, 8, 856-871. 

M., Khadem, S., Leek, D. M., Arya, P. (2006) Part 1. Modular approach to obtaining diverse tetrahydroquinoline-derived polycyclic skeletons for use in high-throughput generation of natural-product-hke chemical probes. Journal of Combinatorial Chemistry, 8, 715-734. 

Nagashima, T. and Zhang, W. 2004. Fluorous parallel synthesis of an A-aUcylated dihydropte-ridinone library. Journal of Combinatorial Chemistry, 6 942-49. 

Scharn, D., Wenschuh, H., Reineke, U., Mergener, J.S., and Germeroth L. 2002. Spatially addressed synthesis of amino- and amino-oxy-substituted 1,3,5-triazine arrays on polymeric membranes. Journal of Combinatorial Chemistry, 2 361-69. 

Kofoed, J. and Reymond, J.L. (2007) A general method for designing combinatorial peptide libraries decodable by amino add analysis. Journal of Combinatorial Chemistry, 9,1046-1052. 

Combinatorial Chenristry and High-Throughput Screen ing—Bentham Publishers Drttg Discovery Today—Reed Elsevier Journal of Chemical Information and Cumpnter Sci ences—American Chemical Socicly Journal of Combinatorial Chemistry—American Chernica Society... 

To assist medicinal chemists in their understanding of combinatorial chemistry and to help with the acceptance of a universally understood language, a Glossary of Combinatorial Chemistry Terms was published in Pure and Applied Chemistry and subsequently, in the Journal of Combinatorial Chemistry. This ensures its use within the American Chemical Society as a standard glossary of terms. Further work is focused on producing an opinion document on the legal implications of patenting virtual libraries. This is a very important issue which has profound implications for research and development in the pharmaceutical industry. 

The official Web site of ACS. Features a molecule of the week, a discussion board, polls, news, and calendar of events. A separate member s section features election results, membership information, resources, and benefits. Registered users can create their own personalized page. An Educators Students page presents suitable-level essays on chemistry-related issues. There is free access to recent articles from Industrial Engineering Chemistry Research, the Journal of Combinatorial Chemistry, and the 125 most-cited journals of the ACS publications program. 

Ghose, A.K., Viswanadhan, V.N. and Wendoloski, J.J. (1999) A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases. Journal of Combinatorial Chemistry, 1, 55-68. 

---