Ito coil planet centrifuge

Martin, D.G. Peltonen, R.E. Nielsen, J.W. Preparative resolution of an actinomycin complex by countercurrent chromatography in the ito coil planet centrifuge. J. Antihiot. 1986, 39, 721. 

Ito, Y., Efficient preparative counter-current chromatography with a coil planet centrifuge, J. Chromatogn, 214, 122, 1981. 

Ito, Y. Cross-axis synchronous flow-through coil planet centrifuge free of rotary seals for preparative counter-current chromatography. Part I Apparatus and analysis of acceleration. Sep. Sci. Technol. 1987, 22, 1971. 

Shinomiya, K. Menet, J.-M. Fales, H.M. Ito, Y. Studies on a new cross-axis coil planet centrifuge for performing counter-current chromatography. I. Design of the apparatus, retention of the stationary phase, and efficiency in the separation of proteins with polymer phase systems. J. Chromatogr. 1993, 644, 215. 

Shinomiya, K. Sasaki, Y. Shibusawa, Y. Kishinami, K. Kabasawa, Y. Ito, Y. Countercurrent chromatographic separation of hippuric acid and related compounds using cross-axis coil planet centrifuge with eccentric coil assemblies. J. Fiq. Chromatogr. Relat. Technol. 2000, 23, 1575. 

Harada, R. Ito, Y. Kimura, E. A new method of osmotic fragility test of erythrocytes with coil planet centrifuge. Jpn. J. Physiol. 1969, 19, 306-314. 

Ito, Y. Aoki, I. Kimura, E. Nunogaki, K. Nunogaki, Y. New micro liquid-liquid partition techniques with the coil planet centrifuge. Anal. Chem. 1969, 41, 1579-1584. 

Ito, Y. Menet, J.-M. Coil Planet Centrifuges for High-Speed Countercurrent Chromatography. In Countercurrent Chromatography Menet, J.-M., Thiebaut, D., Eds. Marcel Dekker New York, 1999 87-119. 

Ito, Y. Carmeci, P. Sutherland, I.A. Nonsynchronous flow-through coil planet centrifuge applied to cell separation with physiological solution. Anal. Biochem. 1979, 94, 249-252. 

Ito, Y. Bramblett, G.T. Bhatnagar, R. Huberman, M. Leive, L. Cullinane, L.M. Groves, W. Improved nonsynchronous flow-through coil planet centrifuge without rotating seals. Principle and application. Sep. Sci. Technol. 1983, 18 (1), 33 -48. 

Okada, T. Metcalfe, D.D. Ito, Y. Purification of mast cells with an improved nonsynchronous flow-through coil planet centrifuge. Int. Arch. Allergy Immunol. 1996, 109, 376-382. 

Ito, Y. Kitazume, E. Bhatnagar, M. Trimble, F. Crossaxis synchronous flow-through coil planet centrifuge (Type XLL). I. Design of the apparatus and studies on retention of stationary phase. J. Chromatogr. 1991, 538, 59. 

Ito, Y, Foam countercurrent chromatography New foam separation technique with flow-through coil planet centrifuge, Separ. Sci. 11 201 (1976). 

J. L. Sandlin and Y. Ito, Large-scale preparative countercurrent chromatography with a coil planet centrifuge,/. Liquid Chromatogr. 5(12) 2153-2171 (1985). Y. Ito and R. Bhatnagar, Improved scheme for preparative CCC with a rotating coil assembly, /. Chromatogr. 207 171-180 (1981). 

A further improvement is to move one solvent past the other in the opposite direction. This countercurrent technique can not only separate several compounds from a sample but can separate them from each other at the same time. This is then a combination of an extraction and a chromatographic separation. The coil planet centrifuge, developed by Ito, is discussed in Chapter 11. 

Figure 11-1. Diagram of a horizontal flowthrough gear-driven coil-planet centrifuge. (Courtesy - Mandava, N, and Ito, Y., Countercurrent Chromatography. Theory and Practice, Marcel Dekker, New York, 1988)...

Chen, R H., Hochlowski, J. E, McAlpine, J. B., and Rasmussen. R. R. (1988) Separation and punfication of macrolides using the Ito multi-layer horizontal coil planet centrifuge. J. Liquid Chromatogr. 11,191-201. 

Purifications of elfamycins have been described in the literature usiog Craig distribution (2,34), chromatography on Sephadex LH-20 (2,14,26) and Ambedite XAD-2 (10,17,19,26), supercritical fluid extraction (37), and chromatography on an Ito multilayer coil planet centrifuge (26,38). and nmr assignments of most elfamycins have been accomplished (3,24,26,32). The characteristic uv spectra permits some differentiation (12) and bathochromic shifts associated with Al " complexation have been used to quantify efrotomycin (2, R = CH ) iu feed premixes (39,40). 

Ito Y (1981) New continuous extraction method with a coil planet centrifuge. Journal of Chromatography 207 161-169. 

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