Isopropanol/isopropylamine

Epoxy-3-[p-(/3-methoxyethyl)-phenoxy] -propane (16.7 g) was dissolved in 50 ml isopropanol and mixed with 20 ml isopropylamine. The mixture was heated in an autoclave on... 

The sympatholyfics of this type interfere with the /3i- and /S2-adrenoceptor subtypes. Via this mechanism the stimulating influence of the sympathetic nervous system on the heart and the metabolism and its inhibiting influence on smooth muscle is blocked. /3-Adrenoceptor blocking agents, or /3-blockers, mostly have a typical isoproterenol-like structure with an isopropylamine or a tertiary butylamine group and a substituted phenoxy moiety bound to the isopropanol backbone. The substituents determine the physicochemical properties of the particular drug and thereby its pharmacokinetic proflle. 

Dihydroxy benzoic acid trinexapac Di-isobutylamine butylate Di-isopropanol amine fenpropimorph Di-isopropylamine diallate, triallate Di-isopropylaniline diafenthiuron... 

N.Isopropylaniline (1) Isopropylamine + benzene chloride (2) Aniline HC1 + isopropanol... 

A mixture of 72% isopropanol and 28% isopropylamine (a binary nerve-gas component). Including mustard gas in oh product . 

Systematic method development guidelines akin to those available for HPLC have not been developed. However, details beyond the scope of this chapter are available.Separation conditions should be evaluated based on the polarity of the solute and the polarity of the stationary phase. Stationary-phase polarity increases in the order C18phenylnonpolar solutes on nonpolar stationary phases, separation may be achieved using pure carbon dioxide. As solute or stationary-phase polarity increases, carbon dioxide modified with methanol (or isopropanol, ethanol, or acetonitrile) or carbon dioxide modified with solvent and an additive such as TFA, acetic acid, triethylamine, or isopropylamine (0.5% or less) is required. 

Two successive 1,2-hydride shifts can be ignored, as the initially formed secondary carbonium ion would give rise to some isopropanol. In addition, deamination of isopropylamine does not yield n-propanol. The intermediacy of a protonated cyclopropane is excluded as no label is found on the 2-carbon... 

Isopropanol is used in the production of other chemicals such as derivative ketones, isopropylamines, and isopropyl esters. The use of isopropanol in the production of monoisopropylamine for herbicides (primarily glyphosate) continues to be the fastest growing segment (Anonymous 2001b). A minor use for isopropanol is to serve as a feedstock for the production of acetone to meet the demand in excess of the coproduct acetone from phenol production. However, isopropanol is also produced from crude acetone, which is generated as a by-product of propylene oxide manufacture (Anonymous 2001b). 

Also obtained by reaction of isopropylamine with a-bromo-4-benzoyloxyaceto-phenone in isopropanol [4724]. 

Also obtained by reaction of a-brcmo-p-benzo-yloxy-acetophenone with isopropylamine in isopropanol between 20° and 30° for 2 h, then treatment of the formed base with refluxing 15% hydrochloric acid solution (64%) [4724]. 

Obtained by condensation of a-chloro-3,4-dihydroxy-acetophenone with isopropylamine [4803] in isopropanol at 65-70°. The amino ketone which separated was treated with concentrated hydrochloric add (54%) [4795], (46%) [4804]. 

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