Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Isoprenylated flavonoids from medicinal plants

CHEMISTRY AND BIOLOGICAL ACTIVITIES OF ISOPRENYLATED FLAVONOIDS FROM MEDICINAL PLANTS (MORACEOUS PLANTS AND GLYCYRRHIZA SPECIES)... [Pg.199]

Prenylated flavonoids contain one or two isoprenyl, geranyl, dimethylallyl, and lavandulyl on the skeleton. They have limited distribution and are mostly isolated from the Moraceae family. Chi et al. isolated 19 prenylated flavonoids from six different genera of Chinese medicinal plants and evaluated inhibition activities on eicosanoid metabolisms with multiple cell line models [189]. Two 8-lavandulylated flavanones, kurarinone and sophoraflavanone G, were discovered to be dual inhibitors. They possessed the most potent COX-1 inhibitory activities with IC50 less than 1 pM comparable with that of indomethacin. Sophoraflavanone G isolated from the roots of Sophora flavescense Art (Fabaceae) also had potent 5-LOX inhibition activity with an IC50 below 0.25 pM. [Pg.705]


See other pages where Isoprenylated flavonoids from medicinal plants is mentioned: [Pg.202]    [Pg.207]   
See also in sourсe #XX -- [ Pg.199 ]

See also in sourсe #XX -- [ Pg.28 , Pg.199 ]




SEARCH



Flavonoids from

From plants

Isoprenyl

Medicinal plants

Medicine, plants

© 2024 chempedia.info