Isoniazid chemical structure

This drug has some similarities in its chemical structure to isoniazid but acts in a completely different way. It is used to treat high blood pressure which it does by dilating blood vessels. This means that there is less resistance to the blood flowing through the small vessels, the capillaries, and so the pressure in the blood system (cardiovascular system) is lower. [Pg.71]

On the other hand, NAD (nicotinamide adenine dinucleotide), known as coenzyme I and II, and NADP (nicotinamide adenine dinucleotide phosphate) are derivatives of nicotinamides. The chemical structures of NAD, NADP, and the reduced form of these alkaloids, NADH and NADPH (nicotinamide adenine dinucleotide phosphate reduced), are shown. Isonicotinic acid hydrazide (INH or isoniazid) is a synthetic derivative of nicotinic acid and has potent antibacterial activity against Mycobacterium tuberculosis (Section 13.2) [1,2]. [Pg.183]