Iso-Propyl acetate

Methyl formate. Ethyl formate Methyl acetate Iso-propyl formate Ethyl acetate Methyl propionate "-Propyl formate Iso-propyl acetate Methyl iso-butyrate Iso-butyl formate. Ethyl propionate M-Propyl acetate. Methyl butyrate. ... 

A typical elution profile the separation of saturated esters by gas-liquid chromatography 1. methyl formate 2. methyl acetate 3. ethyl formate 4. ethyl acetate 5. -propyl formate 6. iso-propyl acetate 7. w-butyl formate 8. sec-butyl acetate 9. iso-butyl acetate 10. n-butyl acetate... 

Ethyl acetate. n-Propyl acetate iso-Propyl acetate n-Butyl acetate iso-Butyl acetate sec.-Butyl acetate tert.-Butyl acetate n-Amyl acetate iso-Amyl acetate n-Hexyl acetate cycZoPentyl acetate. cycioHexyl acetate. ... 

Amyl, butyl, and iso-propyl acetates are all made from acetic acid and the appropriate alcohols. All are useful lacquer solvents and their slow rate of evaporation (compared to acetone or ethyl acetate) prevents the surface of the drying lacquer from falling below the dew point, which would cause condensation on the film and a mottled surface appearance (blushing). Other esters of importance are used in perfumery and in plasticizers and include methyl salicylate, methyl anthranilate, diethyl-phthalate, dibutyl-phthalate, and di-2-ethylhexyl-phthalate. 

The fact that ethyl formate, ethyl acetate, ethyl propionate, n-propyl formate, n-propyl acetate, iso-propyl acetate and methyl n-butyrate all... 

Fig. 14. The cool flame limit curves of equimolar ester oxygen mixtures in an HF-treated spherical pyrex vessel, diameter = 10.1 cm 45]. (1) Ethyl acetate. (2) iso-Propyl acetate. (3) Methyl n-butyrate. (4) n-propyl acetate.

Huisgen also found that in acetic acid as solvent the three reactions lead to much the same proportion of n- and iso-propyl acetates. It seems probable that the carbonium ions are here formed predominantly within ion pairs. Most likely, however, ion pair exchange occurs with the acidic solvent leading almost exclusively to propyl-acetate pairs as the carbonium ion intermediates. 

Iso-Propyl acetate. Use 40 g. (61 ml.) of tso-propyl alcohol, 160 g. of glacial acetic acid and 2 g. of concentrated sulphuric acid. Reflux for 18 hours. Proceed as for n-propyl acetate. B.p. 87-88°. Yield 31 g. 

After protection, the C4" hydroxy group is oxidized to the ketone, which can be achieved with dimethyl sulfoxide and phenyldichlorophosphate (or oxalyl chloride) in the presence of triethylamine. Subsequently, the reductive amination of the ketone can be performed with methylamine, acetic acid and sodium borohydride in methanol. Alternatively, the ketone is treated with heptamethyldisilazide and zinc chloride in iso-propyl acetate, followed by reduction of the intermediate imine with sodium borohydride in the presence of ethanol. This transformation leads to the (R)-configured 4"-desoxy-4"-epi-methylamino derivative as the predominant product, with only very small amounts of the 4"-(S)-isomer being... 

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