Ipecac syrup contraindications

Basic and advanced life-support measures should be utilized as necessary. Decontamination with syrup of ipecac is contraindicated due to the likelihood for developing rapid onset seizures. Gastric decontamination with activated charcoal may be considered for substantial recent ingestions. Fluid and electrolytes need to be frequently monitored and replaced as necessary. 

Activated charcoal is the preferred method of decontamination. The use of syrup of ipecac is contraindicated because of the potential for serious CNS and respiratory depression. Naloxone, a specific opioid antagonist, should be used to reverse significant respiratory depression. Nalmefene and naltrexone are... 

Gastrointestinal decontamination should be considered for patients who have ingested pentazocine only after initial supportive care has been provided and airway control has been assured. Activated charcoal (1 gkg ) may be administered. Syrup of ipecac is contraindicated after overdose with pentazocine due to the potential for rapid clinical deterioration. Gastric lavage is not indicated. Naloxone can be infused in an attempt to reverse respiratory and CNS depression. Naloxone administration may precipitate opioid withdrawal and should be administered slowly. Recent case series have demonstrated that naloxone may not result in clinical improvement in the majority of patients who have overdosed on pentazocine. 

Ipecac syrup sold in the United States must be in packages of less than 1.0 ounce and labeled with contraindications for use in unconscious persons, or following the consumption... 

Upon exposure by ingestion, where corrosive injury is absent, the decontamination to prevent further absorption may be achieved by use of activated charcoal. Emesis by syrup of ipecac may be considered, but not preferred. Next, milk should be given to drink. Gastric lavage and emesis are contraindicated in the presence of esophageal injury. In the case of dermal exposure, the poison should be removed by washing the affected skin or mucous membrane with copious amounts of water for at least 15 min. 

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