Cellulose ion exchange

Schober, R. and Heimburger, N. i960. Fractionation of Na-caseinate by column chromatography on ion-exchange-cellulose. Milchwissenschaft 15, 607-609 (German). 

E. M. Southern, An improved method for transferring nucleotides from electrophoresis strips to thin layers of ion-exchange cellulose, Anal Biochem. 1974, 62, 317-318. 

Rocha,J.C., Toscano, I.A.S. and Cardoso, A.A. (1997) Relative lability of trace metals com-plexed in aquatic humic substances using ion-exchanger cellulose-Hyphan. /. Braz. Chem. Soc., 8, 239-243. 

Cortex Biochem has found interesting applications for magnetizahle particles in analytical fields. Particles of the analytic aid are prepared Ifom a combination of magnetizable materials (iron oxide) and absorbing material (e.g., charcoal, polyacrolein, ion exchange, cellulose). The particles are dispersed in a biological sample to selectively absorb required compounds. After absorption was accomplished, particles with absorbed substance are removed from solution by a magnetized rod. The materials are used for separation of enzymes, protein, cells or bacteria. 

Examples of successful fractionations of aquatic humic substances where only one fractionation mechanism was operative include utilization of the hydrophobic properties of XAD resins (Mantoura and Riley, 1975 Aiken et al., 1979), hydrogen bonding of weak-acid functionalities of humic constituents to weak-base anion-exchange resins (Kim et al., 1976), and use of ion-exchange celluloses for ion-exchange fractionation of aquatic humic substances without hydrophobic matrix adsorption (Sirotkina et al., 1974). These examples of successful fractionations demonstrate the potential for chromatography of aquatic humic substances when fractionations are designed carefully to avoid undesirable interactions. 

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