Iodine-containing compounds

Kulprathipanja, S., Sherman,)., Napolitano, A., and Markovs, J. (2002) Method for treating a liquid stream contaminated with an iodine-containing compound using a cation-exchanged zeolite. U.S. Patent 5,380,428. 

Estimation of protein-bound iodine and tracer studies for the estimation of thyroid function are interfered with by the use of iodine-containing compounds (73). 

Thyroid hormone-producing thyroid carcinoma is an uncommon cause of thyrotoxicosis. Precipitation of thyrotoxicosis by iodine-containing compounds in patients with thyroid carcinoma is rare, but has been attributed to amiodarone in a 77-year-old man with extensive hepatic metastases from a well-differentiated thyroid carcinoma (40). 

Some reduced derivatives of imidazo[2,l-b]-l,3-thiazin-4-one have been described. For example, the reaction of 2-mercaptobenzimidazole with acry-loyl chlorides results in TAs 188 (91MI2). A similar iodine-containing compound (R = H) was synthesized by the cyclization of acid 189 (92MI2) (Scheme 66). 

We previously reported that iodine containing compounds are resistant to oxygen plasma etching, and proposed two-level resist systems utilizing a mixture of iodine compounds and a commercially available positive photoresist(3). However, this resist has low resistance to O -RIE. 

For iodine-containing compounds the position is simpler, solid iodine being the sole product of combustion 29 Xhe accuracy... 

The radio-opacity of X-ray contrast media depends on the fact that they contain substances that have high atomic numbers, which absorb X-rays. Bismuth, now largely obsolete, has an atomic number of 83, barium 56. Since the soluble salts of barium are poisonous, the insoluble salt, barium sulfate, is used as a suspension. Soluble contrast media are based on iodine, which has an atomic number of 53. This means that in principle they can have the various adverse effects of other iodine-containing compounds. 

Thus, a search for the chemistry of the element iodine is a different matter from one for the use of the iodine-containing compounds medicinally, and would have to be differently planned. 

Although CHI 3, and several other iodinated compounds, were readily identified by both n.m.r. and m.s. analysis of the crude oil obtained from A. taxiformis, many of the original iodine-containing compounds were found not to survive the chromatographic separation. Carbonyl diiodide was therefore postulated as an artefact that results from the decomposition of CHI 3 during the chromatographic process. Clearly, further work is required to substantiate or refute the possible formation of this compound, as this remains the only claim of its existence in the literature. 

Figure 15.8 The effect of iodine-containing compounds on the growth of Tetrahymena pyriformis, T. pyriformis is cuitured in a soiution of various iodine-containing compounds for 34 h. The growth of the ceiis in various soiutions was shown as oq N/Nq), where N is the number of ceiis after 34 h cuiture and A/q is the number of ceiis at the beginning of the experiment. A high N/Nq indicates a iower toxicity of compound to the ceiis.

Iodine-Containing Compounds Use in Patients with Documented Adverse Reactions... 

Beall et al. (2007) where no reaction occurred following a second exposure to an iodine-containing compound (ami-odarone) after initial exposure to either contrast media or seafood, the reaction is unlikely to be due to the iodine content. There are no reported cases of patients having an anaphylactic or anaphylactoid reaction after receiving ami-odarone with a previous history of reaction to an iodine-containing compound. 

Until more studies are completed and more is known about the mechanism behind reactions to iodine-containing compounds, it is unclear if these responses are true type 1 hypersensitivities. 

The reaction of ASP3S3 and AsP3Sc3 with several iodine-containing compounds, such as CHI3, PI3, NIS, and I2, were carried out in the melt or in CS2 solution by Blachnik and Neto <1997ZFA1043>. The 2,6,7-trithia-l,3,4-triphospha-... 

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