Intraval Sodium

Proprietary Names. Farmotal Intraval Sodium Nesdonal Pentothal Trapanal. 

Pentothal Pentothal Sodium Intraval Sodium ) is a barbiturate used for intravenous induction of anaesthesia, or as an intravenous general ANAESTHETIC for short operations. It is also used as an ANTICONVULSANT in short-term control of convulsive states. 

Thiopental Sodium, 5.Ethyldihydro-5 ( I-methyl-butyl)-2-thioxo-4,6(lH,SH)-pyrimidinedione monosodium salt 5-ethyl-5-iI-methy(butyl)-2-thiobarbituric acid sodium salt thiomebumal sodium penthiobarbital sodium thiopen -tone sodium thionembutal Pentothal Sodium Nesdonal Sodium Intraval Sodium Trapanal Thiothal Sodium. C,.-Hl7N2Na02S mol wt 264.33. C 49.98%, H 6,48%, N 10.60%, Na 8,70%, O 12-11%, S 12.13%. Prepn U.S. pats. 2,153,729 (1939) 2,876,225 (1959). Prepn of nonhygrosopic crystals Hartop, U.S. pat. 3,109,001 (1963 to Abbott). Acute toxicity Christensen, Lee, Toxicol. Appl. Pharmacol. 26, 495 (1973). 

Pentothal sodium (Abbott) Intraval sodium (May and Baker)... 

Pentothal Sodium, Nesdonal Sodium, Intraval Sodium, Trapanal, Thiothal Sodium, Faimotal, Hypnostan, Sandotfaal [1,3]. 

Thiopentone. (Pentothal, Intraval.) 34 g of clean metallic sodium are dissolved in 1 liter of dry ethanol. To this solution add 130 g of ethyl-1-methyl butyl malonic ester. This mixture is stirred, 60 g of powdered thiourea is added and the whole is refluxed for 10 hours. Remove the alcohol by distilling under reduced pressure, dissolve the residue with water and acidify with hydrochloric... 

In general, barbiturates—thiopental in particular—change into soluble form on treatment with bases. Therefore, thiopental often appears in the market under the name sodium thiopental. In this case, the formation of a salt occurs due to the sulfur atom in an enethi-olate form. The most common synonyms for thiopental are pentothal, trapanal, farmotal, intraval, and others. 

Chemotoxicity. The development of modern contrast agents began with the observation by Wallingford et al. (219) that iodo-benzoic acids have very low toxicity. lodina-tion, substitution, and acetylation can modify the acute toxicity of substituted benzoic acids (209,210). For example, amination of sodium benzoate decreases toxicity, and the intrave-... 

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