Internal granule-cell layer

Zheng T, Santi MR, Marlier LNJ-L, Grayson DR. 1993. Expression of the mRNA encoding the (6 subunit of the GABAa receptor occurs in cerebellar granule cells only after completion of migration to the internal granule cell layers. Dev Brain Res 75 91-103. 

Internal Plexiform Layer and Granule Cell Layer. ... 

Abbreviations GL, glomerular layer EPL, external plexiform layer MCL, mitral cell layer IPL, internal plexiform layer GCL, granule cell layer EZ, ependymal zone. 

The axons of the mitral cells give off collaterals within the bulb in the internal plexiform and granule cell layers (Mori et al. 1983). The main axons course predominantly in the lateral olfactory tract which forms at the level of the AOB. These caudally directed axons give off collaterals in the anterior olfactory nucleus (AON) and other regions of olfactory cortex (Figs. 13, 18, 19). Tufted cells collateralize to an even greater extent in the bulb than mitral cells. The intrabulbar association pathway formed by CCK-ergic tufted cells was discussed earlier. 

EP = exposed group (n = 3). OB = olfactory bulb OP = olfactory peduncle ON = olfactory nerve G1 = glomerular layer Epl = external plexi-form layer. Mi = mitral cell layer Ipl = internal plexiform layer GrO = granule cell layer of olfactory bulb Md = medullary layer GrA = granule cell layer of accessory olfactory bulb AOB = accessory olfactory bulb AOE = anterior olfactory nucleus external part AOL = anterior olfactory nucleus, lateral part lo = lateral tract. (Reprinted from Wang et alP 2007 Humana Press Inc.)... 

The synaptic alterations and deficits found in Ho animals is especially interesting in light of reports that such animals also exhibit an increased amount of cell death in the internal granular layer, which may be related to the reduced capacity of granule cells to make the correct number of synapses with their main synaptic targets, the Purkinje cells (Lewis et al., 1976 Rabie et al., 1979a). 

Figure 5.2 PolyPs in different compartments of the cells of Saccahromyces cerevisiae (lead staining) (Vorfiek et al., 1982) (a) PolyP in vacuoles (the arrow indicates a metachromatic granule) (b) PolyP in a cell nucleus (the arrow indicates the nuclear membrane) (c) PolyP in internal cell wall layers at phosphate overplus (d) PolyP in vacuoles after phosphate overplus the scale bars are equal to 0.5 /xm.

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