Interfacial reactions self-assembled monolayers

Although Eq. (23) was derived for a one-step heterogeneous ET reaction, it was shown to be applicable to more complicated substrate kinetics (e.g., liquid-liquid interfacial charge transfer [38, 39, 67], ET through self-assembled monolayers [68, 69], and mediated ET in living cells [70-73]). The effective heterogeneous rate constant obtained by fitting experimental approach curves to Eq. (23) can be related to various parameters, which determine the rates of those processes, as discussed in the referred publications. 

Interfacial reactions on surfaces are becoming increasingly important due to their widespread applications. Self assembled monolayers (SAMs) provide excellent platforms to study these reactions. This review focuses on the various organic reactions carried out on these SAMs. Challenges and limitations of organic reactions at surfaces are discussed. Emerging biocatalytic techniques for carrying out surface reactions are reviewed. 

Self-assembled monolayers (SAMs) are perhaps the best model for studying these interfacial reactions. Figure 1 shows an idealized view and stmctural model of a SAM on a metal substrate. SAMs are defined as monomolecular films of a surfactant formed spontaneously on a substrate upon exposure to a surfactant solution. Virtually any functional group can be introduced in these monolayers... 

Self-assembled monolayers of a hydroqninone-terminated alkanethiol onto a gold snrface interfacial electrochemistry and Michael-addition reaction with glutathione, M. Shamsipur, S. H. Kazemi, A. Alizadeh, et al., J. Electroanal. Chem., 2007, 610, 218. 

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