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Interconnected Architecture of the Chimney and Roof Regions

Amino acid structure in the upper lip/left lip/roof region is similar in all Y-family DNA polymerases, for which X-ray structures [22-32] or modeled structures [37, 116, 119] exist. [Pg.369]

The no-adduct control had a similar primer-3 -0-Pa-dCTP distance (around 3.7 A). [Pg.369]

These observations provide a reasonable rationale for why Pol IV preferentially does cellular dCTP insertion in cells, since a reasonable adduct-dG dCTP structure emerges with near reaction-ready distances between primer-3 -0 and Pa-dCTP. [Pg.370]

See other pages where Interconnected Architecture of the Chimney and Roof Regions is mentioned: [Pg.368]   


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Chimneys

Interconnect

Interconnected

Interconnected region

Interconnections

Interconnects

Roofing

Roofs

The Region

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