Integrated chemical and biological

One of the main problems for the annotation and classification of the biological space is the lack of a standard scheme for all protein families. Even within families, different classification schemes coexist and are being used by different research communities. This aspect hampers enormously any chemogenomic initiative aimed at integrating chemical and biological spaces with novel computational techniques. The following provides an overview of the classification schemes currently in use for the main therapeutically relevant protein families. 

Armstrong, D.E. and G. Chesters (1968). Adsorption catalyzed chemical hydrolysis of atrazine. Environ. Sci. Technol., 2 683-689. Arnold, S.M., W.J. Hickey, R.F. Harris, and R.E. Talaat (1996). Integrating chemical and biological remediation of atrazine and i-tnazine-containing pesticide wastes. Environ. Toxicol. Chem., 15 1255-1262. 

Ollis DF (2000) On the Need for Engineering Models of Integrated Chemical and Biological Oxidation of Wastewaters, Conference Proceedings of the 2" International Conference on Oxidation Technologies for Water and Wastewater Treatment,... 

Naval leadership should commit to strengthening and integrating chemical and biological weapons defense considerations into all naval functions. 

There is an increasing interest to integrate chemical and biological sensors in microsystems. The miniaturization of analytical systems allows rapid and efficient detection and separation. For the measurement samples are used with volumes down to the nano and femtoliter range. 

J. M. Holland, Integrated chemical and biological testing of synthetic oils and effluents— carcinogenesis testing. Proceedings of Symposium on Potential Health and Environmental... 

Figure 7. Integrated Chemical and Biological Sensor Platform.

An Integrated Chemical and Biological Data Retrieval System for Drug Development... 

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