Insulin resistance modulation

L. Pirola, A. M. Johnston, E. van Obberghen (2003). Modulators of insulin action and their role in insulin resistance. Int. J. Obes. 27(suppl. 3) S61-S64. 

A. R. Saltiel, J. A. Fox, P. SherUne, P. Cuatrecasas (1986). Insulin-stimulated hydrolysis of a novel glycoUpid generates modulators of cAMP phosphodiesterase. Science 233 967-972. P. R. Shepherd, B. B. Kahn (1999). Glucose transporters and insulin action—implications for insulin resistance and diabetes melUtns. N. Eng. J. Med. 341 248. 

Kalupahana, N. S., Claycombe, K., Newman, S. J., Stewart, T., Siriwardhana, N., Matthan, N., Lichtenstein, A. H., and Moustaid-Moussa, N. (2010b). Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation. J. Nutr. 140,1915-1922. 

Yosefy C, Magen E, Kiselevich A, Priluk R, London D, Volchek L, Viskoper JR. Rosiglitazone improves, while glibenclamide worsens blood pressure control in treated hypertensive diabetic and dyslipidemic subjects via modulation of insulin resistance and sympathetic activity. J Cardiovasc Pharmacol 2004 44 215-22. 

Hofmann, C., Lorenz, K, Braithwaite, S. S., Colca, J. R., Palazuk, B.J., Hotamisligil, G. S., and Spiegelman, B. M. (1994). Altered Gene Expression for Tumour Necrosis Factor-A and Its Receptors During Drug and Dietary Modulation of Insulin Resistance. Endocrinology 134, 264—270. 

Urea, the end product of nitrogen metabolism, accumulates rapidly in ARF. Most patients with ARF have a primary stressful illness that results in ureagenesis, and thus protein breakdown is markedly accelerated. Protein catabolism in ARF may be stimulated as the result of insulin resistance, metabolic acidosis, circulating proteases and inflammatory mediators, and the effects of uremic toxins. The mechanism may be direct, via modulation of protein synthesis, or indirect, by inhibiting the action of anabolic hormones. ... 

Riserus U, Amlov J, Berglimd L. Long-term predictors of insulin resistance role of lifestyle and metabolic factors in middle-aged men. Diabetes Care, 2007, 30 2928 -33. Lopez S, Bermudez B, Pacheco YM, et al. Distinctive postprandial modulation of beta cell fimction and insulin sensitivity by dietary fats monoimsaturated eompared with saturated fatty acids. Am J Clin Nutr. 2008, 88 638-644. 

Caricilli AM, Picardi PK, de Abreu LL, et al. Gut microbiota is key modulator of insulin resistance in TLR 2 knockout mice. PLoS Biol. 2011,-9 el001212. 

Cani PD, Amar J, Iglesias MA, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes. 2007 56(7) 1761—1772. Neyrinck AM, Possemiers S, Verstraete W, De Backer F, Cani PD, Delzenne NM. Dietary modulation of clostridial cluster XlVa gut bacteria (Roseburia spp.) by chitin-glucan fiber improves host metabolic alterations induced by high-fat diet in mice. / Nutr Biochem. 2012 23... 

---