Insulin metabolism oral contraceptives

It is by no means impossible that the overall effect of oral contraceptives on the arterial system is exercised through a complex of different mechanisms. In this respect it is worth recalling the insulin resistance syndrome or metabolic syndrome, which comprises a set... 

Carbohydrate metabolism was known at an early date to be affected by combined oral contraceptives. A mild to moderate degree of insulin resistance was found in some investigations (167,168). However, the considerably impaired glucose tolerance described in some users in... 

On the basis of data on metabolism of human monocomponent insulin in 6 women on oral contraceptives and 10 controls it has been suggested that capillary permeability to insulin is increased as well as the peripheral degration in women on oral contraceptives (119 ). The results indicate a significant alteration in insulin metabolism which may contribute to the impairment of carbohydrate tolerance seen in some women taking combined oral contraceptives. 

Srivastava, M. C., Oakley, N. W., Tompkins, C. V., Sonksen, P. H. and Wynn, V. (1975) Insulin metabolism, insulin sensitivity and hormonal responses to insulin infusion in patients taking oral contraceptive steroids. Europ. J. din. Invest. (Berl.), 5, 425. 

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