Inorganic mercury compounds urine

The metabolite is eliminated mainly in urine and feces it is also excreted in milk. In humans, inorganic mercury compounds have two elimination half-lives one lasts for days or weeks and the other much longer. 

Poisoning by inorganic mercury compounds can lead to reduced production of urine and even to kidney failure. Poisoning by elemental mercury can occur either by inhalation of mercury vapours or ingestion of mercury. The ingestion of mercury manifests by increased sahvation, a metallic taste in the mouth, swollen... 

New York Developing capacity to monitor for polyaromatic hydrocarbons (PAHs) in urine, polybrominated diphenyl ethers (PBDEs) in serum, organochlorine pesticides in serum, volatile organic compounds (VOCs) in blood, cotinine in saliva, trace elements in blood and urine, inorganic mercury in blood and to generate data on exposure to persistent organic pollutants (CDC 2005). 

Both lead and mercury speciation has been performed by Shum and coworkers [43]. Direct injection nebulization and an ion-pair separation with a microbore LC column were used with ICP-MS detection. A mobile phase of 20 80% v/v ace-tonitrile/water with 5 mM ammonium pentanesulfonate ion pairing reagent at pH 3.4 was used to separate inorganic lead, inorganic mercury, and three organomer-cury species. Detection limits, based on peak area calculations, were 0.2 pg of Pb for all the lead compounds and 7-18 pg of Hg for the mercury compounds. Spiked urine samples were analyzed to evaluate the performance of the method. 

Flame atomisation is not necessary for the atomic absorption spectrophotomehy of mercury. The cold vapour technique described here employs a reduction vessel (which may be purchased) to produce mercury vapour the vapour is led to a quartz absorption cell within the atomic absorption inshument. The method is applicable to inorganic and organic mercurial compounds in urine. 

Mercury will cross the placental barrier. In mammalian tissue, organic mercury, especially alkyl mercury, is converted to inorganic forms but not vice versa. Inorganic forms of mercury (not organic forms) induce a metallothionein. Inorganic mercury concentrates mainly in the kidney. Organic mercury compounds, being lipid soluble, concentrate in adipose tissue and the brain. Elimination is primarily in the urine and the feces, with small amounts in breath, sweat, and saliva. 

Following exposure to metallic mercury, the elimination of mercury can occur via the urine, feces, and expired air. Following exposure to inorganic mercury (mercuric), mercury is eliminated in the urine and feces. Organic mercury compounds are excreted predominantly via the feces in humans. In animals, methylmercury is excreted in the feces, and phenylmercury compounds are initially excreted in the feces and then in the urine. Organic mercury compounds are excreted predominantly in the inorganic form. Both inorganic mercury and methylmercury are excreted in breast milk. 

During the first few days after intravenous dosing, phenylmercury compounds are also eliminated primarily in the feces as a result of biliary secretion and its concentration in the gastrointestinal tract (mucosa and lumen) (Berlin and Ullberg 1963). The initial urinary excretion of phenylmercury represents primarily the parent compound (Gage 1964). Several days after exposure, however, elimination is primarily in the urine, which contains predominantly inorganic mercury (Gotelli et al. 1985). 

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