Informatic tools development

SNPper is a Web-based tool developed by the Children s Hospital Informatics Program, Boston [31]. The SNPper tool maps dbSNP refSNPs to known genes, allowing SNP searching by name (e g., using the dbSNP rs name) or by the golden path... 

The CSD-related scientific and software tools developed for polymorph risk mitigation, and cocrystal design, are the central focus of this chapter. We begin with a brief summary of the CSDS, and then discuss (i) the development and application of H-bond propensity analysis, (ii) the study of H-bond landscapes and (iii) informatics-based cocrystal screening. In each case we provide case studies to exemplify the methodology. Ongoing development areas and new opportunities are noted in the section Conclusions and Outlook . 

With the coupling of advanced instrumentation and new technologies and informatics tools, the field of proteomics has great potential in disease detection, drug development, and basic research on proteins. 

I. InfoChem (http //www.infochem.de/en/company/index.shtml InfoChem GmbH is a software company for chemo-informatics founded in 1989 and based in Munich (Germany). InfoChem develops and distributes structure and reaction databases as well as software tools required for these applications. 

Besides the tools, there is a significant effort required to maintain and develop the necessary Informatics capabilities, which are critical to effectively using these HT tools. This infrastructure does not normally exist for conventional tools therefore additional resources are often required. 

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