Infiltration analysis

As a consequence of the inhalation of mineral dusts, infiltration into the lung of inflammatory phagocytic cells, namely PMN and macrophages, occurs (Rola-Pleszczynski et al., 1984). Analysis of the cell populations of the rat pleural cavities after injection with asbestos and silica dust also showed both degranulation and reduction of the mast cell population (Edwards etal., 1984), and it is of interest to note that histamine augments the particle-stimulated generation of macrophage superoxide production (Diaz et al., 1979). 

Fig. 1.4 Protein blot analysis of C5-1 assembly in agroinfiltrated alfalfa leaves. Total leaf soluble proteins, extracted 4 days after infiltration were separated by SDS-PAGE under non-reducing conditions and blotted onto a PVDF membrane. Polyclonal antimouse IgGs were used for detection. Purified C5-1 was mixed with total soluble proteins from control infiltrated alfalfa leaves and loaded as a standard.

A radically new stage of development of lateral models is related to the application of PT methodology. The term percolation was introduced by Broadbent and Hammersley [225] to describe the new class of mathematical problems connected to the analysis of infiltration of liquids or the path of an electrical current through a labyrinth of bonded and nonbonded elements. This theory has become very fashionable in various fields of physics, chemistry, and technical applications (e.g., a problem of displacement of oil from a porous medium [8,223,226,227]). The basics of this theory has been comprehensively discussed in several reviews [121,228-232] and monographs [8,233,234],... 

Respiratory Effects. Pleural effusions and alveolar infiltrations were noted in a man who had washed his hair with an unknown amount of diesel fuel (Barrientos et al. 1977). The relative contributions from inhalation and dermal exposure could not be distinguished in this case. There was no throat irritation in six volunteers following a 15-minute exposure to a concentration reported to be 140 mg/m of deodorized kerosene vapor (Carpenter et al. 1976). The authors used a hot nichrome wire for the volatilization of their test material and reported that the concentration was probably the "highest attainable concentration at which vapor analysis is representative of liquid analysis." The air saturating concentration of kerosene is considered to approximate 100 mg/m (room temperature and 760 mmHg) and is dependent on the constituents of the mixture. 

Roberts, P. J., and Hayry, P. (1976). Sponge matrix allografts A model for analysis of killer cells infiltrating mouse allografts. Transplantation 21, 437-445. 

Another study in Fischer rats demonstrated that MSCs do not elicit an immune response after transplantation in immunocompetent recipients. Syngeneic Fischer MSCs or allogeneic ACI MSCs were implanted via an osteoconductive matrix into the bilateral femoral gap of Fischer rats who were then sacrificed at 3, 6 and 12 weeks post-implantation (n = 4 per time point). Histological analysis showed there was no difference between the syngeneic or allogeneic implants. Allogeneic implants did not induce significant inflammatory cell infiltration or stimulate alloreactive T-cell responses [656702]. 

Hanninen O, Hoek G, Mallone S, Chellini E, Katsouyanni K, Kuenzli N, Gariazzo C, Cattani G, Marconi A, Molnar P, Bellander T, Jantunen M (2011) Seasonal patterns in ventilation and PM infiltration in European cities review, modelling and meta-analysis of available studies from different climatological zones. Air Qual Atmos Health 4(3M) 221-233... 

Londono, D.P., Alvarez, J.I., Trujillo, J., Jaramillo, M.M. and Restrepo, B.l. (2002) The inflammatory cell infiltrates in porcine cysticercosis immunohistochemical analysis during various stages of infection. Veterinary Parasitology 109, 249-259. 

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