Infection, temperature increase

It is suggested that one reason why the body temperature increases during an infection is to restrict the iron available to the pathogens. The increase in temperature favours uptake by the immune cells and by the liver (Chapter 18). 

Fever. For unclear reasons, clozapine is associated with benign, transient temperature increases, generally within the first 3 weeks of treatment. Patients taking clozapine who develop fevers should be evaluated for infections, agranulocytosis, and NMS. 

Temperature increases occur during the early stages of mustard poisoning and these, plus the also typical early leukocytosis, should not be taken uncritically as evidence of infection. Later, the white cell count falls, the platelet count falls and finally the red cell count falls. 

In P. falciparum cultures, exposure to elevated temperature increased the adherence of ring-infected red cells to CD36 (but not ICAM-1). .. due to increased expression of PfEMPl [P. falciparum erythrocyte surface... 

Phlebitis is an infection of a blood vessel. Infusion-related phlebitis is characterised by pain, tenderness, erythema, induration, oedema and a local temperature increase. These circumstances may lead to thrombus formation or venous tissue destruction or both. 

The use of a rectal thermocouple carries a potential risk of physical damage to the rectal waU, transfer of any gastrointestinal infections between individuals and contamination of vehicle control animals with traces of test compound from treated animals. In addition, core temperature increases as a result of handling (Gordon 1990), and rectal temperature underestimates true core temperature, for which measurement from the colon is required in the rat (i.e. 6-8 cm past the anal sphincter Gordon 1990). 

Disruption of these defense mechanisms can lead to bacterial colonization or viral infection. Mucus temperature is important in controlling respiratory infections because decreasing below central body core temperature not only impairs ciliary movement,hut also enhances viral replication,- greatly increasing the likelihood of respiratory infection. Drying of airway mucus also increases the possibility of respiratory infection by reducing mucus thickness and impairing mucociliary clearance, i- i--... 

The nurse evaluates the patient daily for a response to therapy, such as a decrease in temperature, the relief of symptoms caused by the infection (such as pain or discomfort), an increase in appetite, and a change in the appearance or amount of drainage (when originally present). Once an infection is controlled, patients often look better and even state that they feel better. It is important to record these evaluations on the patient s chart. The nurse notifies the primary health care provider if signs and symptoms of the infection appear to worsen. 

Sepsis A syndrome characterized by a systemic inflammatory response (abnormal increases in body temperature, heart rate, respiratory rate, and/or white blood cell concentration) caused by infection. 

It has already been noted that the temperature sensitivity of developmental route is different for different isofemale lines when compared at one time point in an infection (Fig. 5.4). If this sensitivity is considered through an infection, it can be seen that the sensitivity increases during an infection (Fig. 5.5) (Harvey et al., 2000) here the difference in the proportion of larvae that develop into free-living females and iL3s at 19 and at 25°C becomes greater as an infection progresses. However, if the temperature sensitivity of larvae passed from immunologically intact animals is compared with that of larvae passed from hypothymic (nude) rats, it can be... 

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