Industrial solvents bromobenzene

Bromobenzene is a toxic industrial solvent that causes centrilobular hepatic necrosis in experimental animals. It may also cause renal damage and bronchiolar necrosis. The study of the mechanism underlying the hepa to toxicity of bromobenzene has been of particular importance in leading to a greater understanding of the role of GSH and metabolic activation in toxicity. 

Bromobenzene is a toxic industrial solvent that is known to produce centrilobular hepatic necrosis through the formation of reactive epoxides. Figure 14.6 summarizes... 

Bromobenzene is used as an industrial solvent, in organic synthesis, and as an additive to motor oils. 

Bromobenzene is an industrial solvent and environmental pollutant, which causes centrilobular hepatic necrosis in rats and mice (Casini et al. 1985 Jollow et al. 

Dipheny[amine (7) is prepared industrially either by heating aniline with aniline hydrochloride at 140 °C under pressure, or by heating aniline with phenol at 260 °C in the presence of zinc chloride. The most convenient laboratory synthesis uses the Ullmann reaction (Scheme 8.9) (see Chapter 10), in which acetanilide is refluxed with bromobenzene in the presence of potassium carbonate and copper powder in nitrobenzene solvent. Triphenylamine is similarly prepared from diphenylamine and iodobenzene. 

Bromobenzene solvent, heavy-duty cleaners Tripropylene glycol n-butyl ether solvent, heavy-duty detergents Sodium xylenesulfonate solvent, heavy-duty industrial cleaners Monochlorotoluene solvent, herbicides... 

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