INDEX reductive alkylation

An Index to types of reactions, e.g. alkylations, stereoselective reductions, cyclizations etc. and... 

On the other hand, comparative analysis of Fi variables gave the relative reduction of SOS-response in preincubated with AR bacterial cells (Table 3). So, repression SOS-response was proportionally to the length of the AR alkyl radical and was Fi = 3.7 (for Ce-AR) and Fi = 7.0 (for C12-AR) that 76.43-40.40 fold lower than the SOS-system activation level in cells exposured only by UV radiation. With reduction of the AR concentration to lO- M is still observed statistically significant differences in the values of induction index (Fi) of the control and experimental samples, although the repression of SOS-response was less expressed. An increase of the AR concentration up to 1(>3 M in the case of Ci-AR and C3-AR led to some suppression, and for the C5-, Ca- and C12-AR to increase the values of R. 

The same types of A-acyl-O-alkyl derivatives can also be used for GC analysis of the simplest oligopeptides (at least dipeptides and tripeptides). Other, obsolete, recommendations on the GC analysis of these compounds include various sequences for their reduction by LiAlH4 into polyaminoalcohols, followed by N-acylation or per-methylation and, finally, silylation of OH groups. For example, A-TFA dipeptide Phe-Phe after reduction and silylation gives the compound (III) with a retention index of 2390 on semistandard-phase Dexsil-300. 

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