INDEX pulmonary toxicity

Hyperoxia was toxic to cultured human pulmonary endothelial cells, with impairment of replicative function (expressed as growth impairment index), monitored by cell number determination and triti-ated thymidine incorporation. 

Properties Colorless liq. char, sweet odor sol. in methanol, toluene, water misc. with acetone, toluene, octane m.w. 114.15 dens. 0.9698 (20 C) f.p. -100 C b.p. 50-52 C flash pt. (OC) 57 C ref. index 1.434 Toxicotogy ACGIH TLV/TWA5 ppm STEL10 ppm (skin) LD50 (oral, rat) 922 mg/kg, (dermal, rabbit) 2550 mg/kg poison by ingestion moderately toxic by Inhalation and skin contact strong skin and eye Irritant can cause CNS depression, pulmonary edema may cause cancer mutation data TSCA listed... 

Properties Wh. to It. yel. orthorhombic cryst. sol. in alcohol, benzene, ether, acetone, carbon disulfide, chloroform sol. 99 g/l in water insol. in pyridine, quinoline fumes in air m.w. 228.13 dens. 3.14 vapor pressure 1 mm Hg (49.2 C) m.p. 73 C b.p. 223.5 C ref. index 1.4600 Toxicology ACGIH TLV/TWA 0.5 mg (Sb)/m LD50 (oral, rat) 525 mg/kg mod. toxic by ing. human pulmonary effects by inh. irritant corrosive experimental reproductive effects mutation data reported TSCA listed Precaution DOT Corrosive material reacts violently with aluminum, potassium, sodium Hazardous Decomp. Prods. Heated to decomp., emits very toxic fumes of chlorine and antimony... 

Properties Colorless to amber liq. m.w. 195.35 dens. 0.92 kg/l (4 C) f.p. < -78 C b.p. 265 C flash pt. (CC) 118 C ref. index 1.4900 Toxicology LD50 (oral, rat) 446 mg/kg LDLo (skin, rabbit) 2 g/kg mod. toxic by ing., skin contact harmful by inh. irritating to skin, eyes, mucous membranes causes bums may cause somnolence, convulsions, acute pulmonary edema TSCA listed Precaution Corrosive... 

Synonyms Methanesulfonic acid, trifluoro-, methyl ester Trifluoromethanesulfonic acid, methyl ester Empirical C2H3F3O3S Properties Colorless to brn. liq. sol. in 95% ethanol insol. in water reacts exothermically with DMSO m.w. 164.10 sp.gr. 1.450 (20/4 C) b.p. 94-99 C flash pt. 38 C ref. index 1.3244 (20 C) Toxicology Toxic by inh., ing., skin contact corrosive causes burns extremely destructive to tissues of eyes, skin, mucous membranes, upper respiratory tract risk of irreversible effects inh. may cause spasm, inflamm./edema of larynx/bronchi, chem. pneumonitis, pulmonary edema may cause burning... 

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