INDEX migraine

A 41-year-old woman presented with pain and pallor in the leg and a sensation of coolness exacerbated by exercise (34). For many years she had been taking a formulation containing ergotamine 1 mg plus caffeine 100 mg, at a dose of one or two tablets daily, for both prophylaxis and treatment of migraine. For 7 days she had also taken clarithromycin (dose is not stated) for a chest infection. Her legs were cool and cyanosed, with no palpable popliteal or foot pulses and an ankle-brachial index of only 0.6 (normal >0.8). 

It seems that the changes in the cerebral autoregulation associated with migraine can strongly modify the multifractality of middle cerebral artery blood flow. The constriction of the multifractal to monofractal behavior of the blood flow depends on the statistics of the fractional derivative index. As the distribution of this parameter narrows down to a delta function, the nonlocal... 

HIV/AIDS human immunodeficiency virus/acquired immunodeficiency syndrome HUI Health Utilities Index HYEs healthy-year equivalents ICC intraclass correlation coefficient KDQOL Kidney Disease Quality of Life instrument MCS mental component summary scale of the SF-36 MOS-HTV Medical Outcomes Study HIV Health Survey MOT Medical Outcomes Trust MSQOL Migraine Specific Quality of Life NHP Nottingham Health Profile PCS physical component summary scale of the SF-36 QALY quahty-adjusted hfe year QOL quahty of life QOLIE Quality of Life in Epilepsy QWB Quality of WeU-Being scale SF-36 MOS 36-Item Short-Form Health Survey SIP Sickness Impact Profile VAS visual analog scale WY well year YHL years of healthy life... 

I Advantages. Valproic acid is available in multiple dosage formulations. It has a wide therapeutic index and can be considered a broad-spectrum AED. It also may be useful in other neurologic or psychiatric disorders, including migraine headache and bipolar-affective disorder. 

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