Amides INDEX

The detour matrix was used to generate a Wiener-like index (Amid and Trinajstic, 1995), named the detour index (Lukovits, 1996), for simple and weighted graphs (Amid and Trinajstid, 1995 Nikolid et al 1990, 1996, 1999 Lukovits, 1996 Trinajstid et al., 1997a, 1997b, 2001 Lukovits and Razinger, 1997). All kinds of distance indices can be generated from the detour matrix (Lukovits, 1996 Nikolid et al., 1999 Todeschini and Consonni, 2000, 2009 Ludid et al., 2001 Randid and Pompe, 2001 Trinajstid et al, 2001). 

See also PBT degradation structure and properties of, 44-46 synthesis of, 106, 191 Polycaprolactam (PCA), 530, 541 Poly(e-caprolactone) (CAPA, PCL), 28, 42, 86. See also PCL degradation OH-terminated, 98-99 Polycaprolactones, 213 Poly(carbo[dimethyl]silane)s, 450, 451 Polycarbonate glycols, 207 Polycarbonate-polysulfone block copolymer, 360 Polycarbonates, 213 chemical structure of, 5 Polycarbosilanes, 450-456 Poly(chlorocarbosilanes), 454 Polycondensations, 57, 100 Poly(l,4-cyclohexylenedimethylene terephthalate) (PCT), 25 Polydimethyl siloxanes, 4 Poly(dioxanone) (PDO), 27 Poly (4,4 -dipheny lpheny lpho sphine oxide) (PAPO), 347 Polydispersity, 57 Polydispersity index, 444 Poly(D-lactic acid) (PDLA), 41 Poly(DL-lactic acid) (PDLLA), 42 Polyester amides, 18 Polyester-based networks, 58-60 Polyester carbonates, 18 Polyester-ether block copolymers, 20 Polyester-ethers, 26... 

The separation was carried out on a TSKgel Amide-80 column 4.6 mm i.d. and 25 cm long with a mobile phase consisting of a 80% acetonitrile 20% water mixture. The flow rate was 1 ml/min and the column was operated at an elevated temperature of 80°C. The saccharides shown were 1/ rhamnose, 2/ fucose, 3/ xylose, 4/ fructose, 5/ mannose, 6/ glucose, 7/ sucrose and 8/ maltose. The analysis was completed in less than 20 minutes. These types of separations including other biomonomers, dimers and polymers are frequently carried out employing refractive index detection. 

Tervalent organophosphorus compounds containing one single P-N bond with the valency of each atom saturated by protons or carbons (but no other heteroatoms) have been known since their discovery by MichaeUs more than one century ago [ 1 ] and named indistinctly as aminophosphanes, phosphanamines, phosphazanes, or phosphinous amides. This last chemical nomenclature is the one used by the Chemical Abstracts Service (CAS) for indexing these compounds and is also the one that best delimits the scope of this review those species derived from the parent H2P-NH2 (phosphinous amide in CAS nomenclature) by partial or total substitution of protons by hydrocarbon radicals (Table 1). 

Examples of the protection of alkynes, carboxylic acids, alcohols, phenols, aldehydes, amides, amines, esters, ketones, and alkenes are also indexed on p. xvii. Section (designated with an A 15A, 30A, etc.) with protecting group reactions are located at the end of pertinent chapters. 

Figure 4 Dynamic dilution of sample for HPLC analysis of amidation/cyclization reaction. Transfer solvent methoxyethanol flow rate 1 ml/min. Detection refractive index.

Table I shows a comparison of free film swell Index results as a function of crosslinker at a constant comonomer level (0.3 moles/kg of polymer). ABDA and AEP gave crosslinking performance Identical to a conventional crosslinker, BNMA. However, derivatives which cannot cycllze, either because the amide has an additional substituent, as In 13, or the chain connecting the amide to the blocked aldehyde Is too short, as In 14, did not exhibit efficient crosslinking. They also showed significant discoloration, presumably due to Increased aldol condensation relative to 1, 2, or BNMA.

CONTENTS List of Contributors. Introduction to the Series An Editor s Forward, Albert Padwa. Preface, Randolph P. Thummel. Cyclooctatetraenes Conformational and ii-Elec-tronic Dynamics Within Polyolefinic [8] Annulene Frameworks, Leo A. Paquette. A Compilation and Analysis of Structural Data of Distorted Bridgehead Olefins and Amides, Timothy G. Lease and Kenneth J. Shea. Nonplanarity and Aromaticity in Polycyclic Benzenoid Hydrocarbons, William C. Herndon and Paul C. Nowak. The Dewar Furan Story, Ronald N. Warrener. Author Index. Subject Index. 

The bourgeoning interest in twisted or atypical amide linkages has resulted in a need to better understand the chemical and physical consequences of disconnection between the amide nitrogen lone pair and its carbonyl. To this end, Mucsi and coworkers recently defined a new amidity index, which shows some promise in quantifying relative amide character . 

Ionic liquids are a class of solvents and they are the subject of keen research interest in chemistry (Freemantle, 1998). Hydrophobic ionic liquids with low melting points (from -30°C to ambient temperature) have been synthesized and investigated, based on 1,3-dialkyl imidazolium cations and hydrophobic anions. Other imidazolium molten salts with hydrophilic anions and thus water-soluble are also of interest. NMR and elemental analysis have characterized the molten salts. Their density, melting point, viscosity, conductivity, refractive index, electrochemical window, thermal stability, and miscibility with water and organic solvents were determined. The influence of the alkyl substituents in 1,2, 3, and 4(5)-positions on the imidazolium cation on these properties has been scrutinized. Viscosities as low as 35 cP (for l-ethyl-3-methylimi-dazolium bis((trifluoromethyl)sulfonyl)amide (bis(triflyl)amide) and trifluoroacetate) and conductivities as high as 9.6 mS/cm were obtained. Photophysical probe studies were carried out to establish more precisely the solvent properties of l-ethyl-3-methyl-imidazolium bis((trifluoromethyl)sulfonyl)amide. The hydrophobic molten salts are promising solvents for electrochemical, photovoltaic, and synthetic applications (Bon-hote et al., 1996). 

The chromatographic capacity factor (AT ) for ester and amide derivatives of 6,6a, 7,8,9,10,10a, 11-octahydro-ll-oxodibenzo[ /]thiepine propionic acid 44, potent antiinflammatory agents, has been studied, since the parameter was widely used for the interpretation of the activity of drugs <2003RRC795>. K, was modeled topologically using molecular redundancy index (MRI), equalized electronegativity (xeq), and van der Waals volume (fw)-... 

Mahfouz, N. M., Omar, F. A., and Aboul-Fadl, T. Cyclic amide derivatives as potential prodrugs II. A-Hydroxymethylsuccinimide-/isatin esters of some NSAIDs as prodrugs with an improved therapeutic index. Eur. J. Med. Chem. 34(7—8) 551—562, 1999. 

A vigorously stirred suspension of 0.2 to 1 mole of sodium amide in 200 ml of xylene, in which were dissolved 0.1 mole of a,a-diphenyl-7-hexamethyleneimino butyronitrile was boiled for 12 hours. Thereupon the excess of sodium amide was decomposed with water and the xylene layer was separated, washed with water and extracted with hydrochloric acid. This acidic extract was made strongly alkaline with concentrated lye and the separated base was extracted with ether. After drying, the ether was evaporated and the l,l-diphenyl-3-hexamethyleneimino propane distilled in vacuo. The boiling point was 170-174°C/1 mm, the refractive index nD20 = 1.56 36, and the density d420 = 1.009. From the oil obtained several acid additions and quaternary ammonium salts can be obtained by reaction with acids containing a non-toxic anion or esters thereof. The hydrochloric acid salt, for instance, melts at 189-192°C, the methiodide at 174-177°C under decomposition. 

Fig. 6. Structural analysis of Vc 1.1 by NMR. (A) The aH secondary shifts. (B) Structural information from NOEs, chemical shift index (CSI), amide exchange, and scalar coupling, are summarized (adapted from ref. 58). (C) A stereoview of the 20 low-energy structures. Some residues are numbered for orientation. (D) Ribbon representation of the peptide the cysteine residues are in yellow. The N-terminus and C-terminus are marked N and C, respectively. (E) The surface of the peptide with selected residues labeled.

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